Recombinant Full Length Human PEX5 Protein, C-Flag-tagged
Cat.No. : | PEX5-1651HFL |
Product Overview : | Recombinant Full Length Human PEX5 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 69.7 kDa |
AA Sequence : | MAMRELVEAECGGANPLMKLAGHFT QDKALRQEGLRPGPWPPGAPASEAA SKPLGVASEDELVAEFLQDQ NAPLVSRAPQTFKMDDLLAEMQQIE QSNFRQAPQRAPGVADLALSENWAQ EFLAAGDAVDVTQDYNETDW SQEFISEVTDPLSVSPARWAEEYLE QSEEKLWLGEPEGTATDRWYDEYHP EEDLQHTASDFVAKVDDPKL ANSEFLKFVRQIGEGQVSLESGAGS GRAQAEQWAAEFIQQQGTSDAWVDQ FTRPVNTSALDMEFERAKSA IELQAELEEMAKRDAEAHPWLSDYD DLTSATYDKGYQFEEENPLRDHPQP FEEGLRRLQEGDLPNAVLLF EAAVQQDPKHMEAWQYLGTTQAENE QELLAISALRRCLELKPDNQTALMA LAVSFTNESLQRQACETLRD WLRYTPAYAHLVTPAEEGAGGAGLG PSKRILGSLLSDSLFLEVKELFLAA VRLDPTSIDPDVQCGLGVLF NLSGEYDKAVDCFTAALSVRPNDYL LWNKLGATLANGNQSEEAVAAYRRA LELQPGYIRSRYNLGISCIN LGAHREAVEHFLEALNMQRKSRGPR GEGGAMSENIWSTLRLALSMLGQSD AYGAADARDLSTLLTMFGLP QSGPTRTRPLEQKLISEEDLAANDI LDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome |
Gene Name : | PEX5 peroxisomal biogenesis factor 5 [ Homo sapiens (human) ] |
Official Symbol : | PEX5 |
Synonyms : | PXR1; PBD2A; PBD2B; PTS1R; RCDP5; PTS1-BP |
Gene ID : | 5830 |
mRNA Refseq : | NM_000319.5 |
Protein Refseq : | NP_000310.2 |
MIM : | 600414 |
UniProt ID : | P50542 |
Products Types
◆ Recombinant Protein | ||
PEX5-4045R | Recombinant Rat PEX5 Protein, His (Fc)-Avi-tagged | +Inquiry |
PEX5-1649H | Recombinant Human PEX5 Protein, His (Fc)-Avi-tagged | +Inquiry |
PEX5-6650M | Recombinant Mouse PEX5 Protein, His (Fc)-Avi-tagged | +Inquiry |
Pex5-4799M | Recombinant Mouse Pex5 Protein, Myc/DDK-tagged | +Inquiry |
PEX5-12654M | Recombinant Mouse PEX5 Protein | +Inquiry |
◆ Lysates | ||
PEX5-3285HCL | Recombinant Human PEX5 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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