Recombinant Full Length Human PILRB Protein, GST-tagged

• Cat.No.: PILRB-636HF
• Product Overview: Recombinant full length Human PILRB(1 a.a. - 227 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ.

Specification

• Description: The paired immunoglobin-like type 2 receptors consist of highly related activating and inhibitory receptors that are involved in the regulation of many aspects of the immune system. The paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This gene encodes the activating member of the receptor pair and contains a truncated cytoplasmic tail relative to its inhibitory counterpart (PILRA), that has a long cytoplasmic tail with immunoreceptor tyrosine-based inhibitory (ITIM) motifs. This gene is thought to have arisen from a duplication of the inhibitory PILRA gene and evolved to acquire its activating function.
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 50.71 kDa
• Protein Length: 227 amino acids
• AA Sequence: MGRPLLLPLL LLLQPPAFLQ PGGSTGSGPS YLYGVTQPKH LSASMGGSVE IPFSFYYPWE LAIVPNVRIS WRRGHFHGQS FYSTRPPSIH KDYVNRLFLN WTEGQESGFL RISNLRKEDQ SVYFCRVELD TRRSGRQQLQ SIKGTKLTIT QAVTTTTTWR PSSTTTIAGL RVTESKGHSE SWHLSLDTAI RVALAVAVLK TVILGLLCLL LLWWRRRKGS RAPSSDF
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: PILRB paired immunoglobin-like type 2 receptor beta [ Homo sapiens ]
• Official Symbol: PILRB
• Synonyms: PILRB; paired immunoglobin-like type 2 receptor beta; paired immunoglobulin-like type 2 receptor beta; FDFACT1; FDFACT2; activating receptor PILRbeta; cell surface receptor FDFACT; activating receptor PILR-beta; cell surface receptor FDFACT1; cell surface receptor FDFACT2; paired immunoglobin-like receptor beta; paired immunoglobulin-like receptor beta
• Gene ID: 29990
• mRNA Refseq: NM_178238
• Protein Refseq: NP_839956
• MIM: 605342
• UniProt ID: Q9UKJ0