Description : |
Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects. Group XII sPLA2s, such as PLA2G12A, have relatively low specific activity and are structurally and functionally distinct from other sPLA2s. |
Source : |
Mammalian cells |
Species : |
Human |
Tag : |
Flag |
Form : |
25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : |
20.9 kDa |
AA Sequence : |
MALLSRPALTLLLLLMAAVVRCQEQ AQTTDWRATLKTIRNGVHKIDTYLN AALDLLGGEDGLCQYKCSDG SKPFPRYGYKPSPPNGCGSPLFGVH LNIGIPSLTKCCNQHDRCYETCGKS KNDCDEEFQYCLSKICRDVQ KTLGLTQHVQACETTVELLFDSVIH LGCKPYLDSQRAACRCHYEEKTDLT RTRPLEQKLISEEDLAANDILDYKD DDDKV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : |
Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : |
Store at -80 centigrade. |
Concentration : |
>50 ug/mL as determined by microplate BCA method. |
Preparation : |
Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : |
Druggable Genome, Secreted Protein |
Protein Pathways : |
alpha-Linolenic acid metabolism, Arachidonic acid metabolism, Ether lipid metabolism, Fc epsilon RI signaling pathway, Glycerophospholipid metabolism, GnRH signaling pathway, Linoleic acid metabolism, Long-term depression, MAPK signaling pathway, Metabolic pathways, Vascular smooth muscle contraction, VEGF signaling pathway |