| Description : |
Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83% identical. It contains a potential calcium-binding site near the N terminus. Alternate splicing results in multiple transcript variants. |
| Source : |
In Vitro Cell Free System |
| Species : |
Human |
| Form : |
Liquid |
| Molecular Mass : |
95.300kDa inclusive of tags |
| Protein Length : |
630 amino acids |
| AA Sequence : |
MDEMATTQISKDELDELKEAFAKVDLNSNGFICDYELHEL FKEANMPLPGYKVREIIQKLMLDGDRNKDGKISFDEFVYI FQEVKSSDIAKTFRKAINRKEGICALGGTSELSSEGTQHS YSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAV GDGIVLCKMINLSVPDTIDERAINKKKLTPFIIQENLNLA LNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLF ADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFH LENSGWQKINNFSADIKDSKAYFHLLNQIAPKGQKEGEPR IDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVS GNPKLNLAFVANLFNKYPALTKPENQDIDWTLLEGETREE RTFRNWMNSLGVNPHVNHLYADLQDALVILQLYERIKVPV DWSKVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVG IGGQDLNDGNQTLTLALVWQLMRRYTLNVLEDLGDGQKAN DDIIVNWVNRTLSEAGKSTSIQSFKDKTISSSLAVVDLID AIQPGCINYDLVKSGNLTEDDKHNNAKYAVSMARRIGARV YALPEDLVEVKPKMVMTVFACLMGRGMKRV |
| Purity : |
Proprietary Purification |
| Storage : |
Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles. |
| Storage Buffer : |
pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione. |
