Recombinant Full Length Human PMEL Protein, GST-tagged
Cat.No. : | PMEL-6849HF |
Product Overview : | Human SILV full-length ORF ( NP_008859.1, 1 a.a. - 661 a.a.) recombinant protein with GST-tag at N-terminal was expressed in Wheat Germ. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 96.7 kDa |
Protein Length : | 661 amino acids |
AA Sequence : | MDLVLKRCLLHLAVIGALLAVGATK VPRNQDWLGVSRQLRTKAWNRQLYP EWTEAQRLDCWRGGQVSLKVSNDGP TLIGANASFSIALNFPGSQKVLPDG QVIWVNNTIINGSQVWGGQPVYPQE TDDACIFPDGGPCPSGSWSQKRSFV YVWKTWGQYWQVLGGPVSGLSIGTG RAMLGTHTMEVTVYHRRGSRSYVPL AHSSSAFTITDQVPFSVSVSQLRAL DGGNKHFLRNQPLTFALQLHDPSGY LAEAD |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | PMEL premelanosome protein [ Homo sapiens (human) ] |
Official Symbol : | PMEL |
Synonyms : | PMEL; premelanosome protein; P1; SI; SIL; ME20; P100; SILV; ME20M; gp100; ME20-M; PMEL17; D12S53E; melanocyte protein PMEL; melanocyte protein Pmel 17; melanocyte protein mel 17; melanocytes lineage-specific antigen GP100; melanoma-associated ME20 antigen; melanosomal matrix protein17; silver locus protein homolog; silver, mouse, homolog of |
Gene ID : | 6490 |
mRNA Refseq : | NM_006928 |
Protein Refseq : | NP_008859 |
MIM : | 155550 |
UniProt ID : | P40967 |
Products Types
◆ Recombinant Protein | ||
PMEL-01H | Recombinant Human PMEL Protein, Tag Free | +Inquiry |
PMEL-2756H | Recombinant Human PMEL protein(371-440 aa), C-His-tagged | +Inquiry |
PMEL-191H | Recombinant Human PMEL Protein, GST-tagged | +Inquiry |
Pmel-4952M | Recombinant Mouse Pmel Protein, Myc/DDK-tagged | +Inquiry |
PMEL-2601H | Recombinant Human PMEL Protein, His-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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