Recombinant Full Length Human PRDX2 Protein, C-Flag-tagged

• Cat.No.: PRDX2-1239HFL
• Product Overview: Recombinant Full Length Human PRDX2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 21.7 kDa
• AA Sequence: MASGNARIGKPAPDFKATAVVDGAF KEVKLSDYKGKYVVLFFYPLDFTFV CPTEIIAFSNRAEDFRKLGC EVLGVSVDSQFTHLAWINTPRKEGG LGPLNIPLLADVTRRLSEDYGVLKT DEGIAYRGLFIIDGKGVLRQ
  ITVNDLPVGRSVDEALRLVQAFQYT DEHGEVCPAGWKPGSDTIKPNVDDS KEYFSKHNTRTRPLEQKLISEEDLA ANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome

Gene Information

• Gene Name: PRDX2 peroxiredoxin 2 [ Homo sapiens (human) ]
• Official Symbol: PRDX2
• Synonyms: PRP; TSA; PRX2; PTX1; TPX1; NKEFB; PRXII; TDPX1; NKEF-B; HEL-S-2a
• Gene ID: 7001
• mRNA Refseq: NM_005809.6
• Protein Refseq: NP_005800.3
• MIM: 600538
• UniProt ID: P32119