Recombinant Full Length Human PSME4 Protein, C-Flag-tagged

• Cat.No.: PSME4-1154HFL
• Product Overview: Recombinant Full Length Human PSME4 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Predicted to enable lysine-acetylated histone binding activity; peptidase activator activity; and proteasome binding activity. Predicted to be involved in DNA repair; proteasomal ubiquitin-independent protein catabolic process; and spermatogenesis, exchange of chromosomal proteins. Located in nucleoplasm.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 211.2 kDa
• AA Sequence: MEPAERAGVGEPPEPGGRPEPGPRG FVPQKEIVYNKLLPYAERLDAESDL QLAQIKCNLGRAVQLQELWP GGLFWTRKLSTYIRLYGRKFSKEDH VLFIKLLYELVSIPKLEISMMQGFA RLLINLLKKKELLSRADLEL PWRPLYDMVERILYSKTEHLGLNWF PNSVENILKTLVKSCRPYFPADATA EMLEEWRPLMCPFDVTMQKA ITYFEIFLPTSLPPELHHKGFKLWF DELIGLWVSVQNLPQWEGQLVNLFA RLATDNIGYIDWDPYVPKIF TRILRSLNLPVGSSQVLVPRFLTNA YDIGHAVIWITAMMGGPSKLVQKHL AGLFNSITSFYHPSNNGRWL NKLMKLLQRLPNSVVRRLHRERYKK PSWLTPVPDSHKLTDQDVTDFVQCI IQPVLLAMFSKTGSLEAAQA LQNLALMRPELVIPPVLERTYPALE TLTEPHQLTATLSCVIGVARSLVSG GRWFPEGPTHMLPLLMRALP GVDPNDFSKCMITFQFIATFSTLVP LVDCSSVLQERNDLTEVERELCSAT AEFEDFVLQFMDRCFGLIES STLEQTREETETEKMTHLESLVELG LSSTFSTILTQCSKEIFMVALQKVF NFSTSHIFETRVAGRMVADM CRAAVKCCPEESLKLFVPHCCSVIT QLTMNDDVLNDEELDKELLWNLQLL SEITRVDGRKLLLYREQLVK ILQRTLHLTCKQGYTLSCNLLHHLL RSTTLIYPTEYCSVPGGFDKPPSEY FPIKDWGKPGDLWNLGIQWH VPSSEEVSFAFYLLDSFLQPELVKL QHCGDGKLEMSRDDILQSLTIVHNC LIGSGNLLPPLKGEPVTNLV PSMVSLEETKLYTGLEYDLSRENHR EVIATVIRKLLNHILDNSEDDTKSL FLIIKIIGDLLQFQGSHKHE FDSRWKSFNLVKKSMENRLHGKKQH IRALLIDRVMLQHELRTLTVEGCEY KKIHQDMIRDLLRLSTSSYS QVRNKAQQTFFAALGAYNFCCRDII PLVLEFLRPDRQGVTQQQFKGALYC LLGNHSGVCLANLHDWDCIV QTWPAIVSSGLSQAMSLEKPSIVRL FDDLAEKIHRQYETIGLDFTIPKSC VEIAELLQQSKNPSINQILL SPEKIKEGIKRQQEKNADALRNYEN LVDTLLDGVEQRNLPWKFEHIGIGL LSLLLRDDRVLPLRAIRFFV ENLNHDAIVVRKMAISAVAGILKQL KRTHKKLTINPCEISGCPKPTQIIA GDRPDNHWLHYDSKTIPRTK KEWESSCFVEKTHWGYYTWPKNMVV YAGVEEQPKLGRSREDMTEAEQIIF DHFSDPKFVEQLITFLSLED RKGKDKFNPRRFCLFKGIFRNFDDA FLPVLKPHLEHLVADSHESTQRCVA EIIAGLIRGSKHWTFEKVEK LWELLCPLLRTALSNITVETYNDWG ACIATSCESRDPRKLHWLFELLLES PLSGEGGSFVDACRLYVLQG GLAQQEWRVPELLHRLLKYLEPKLT QVYKNVRERIGSVLTYIFMIDVSLP NTTPTISPHVPEFTARILEK LKPLMDVDEEIQNHVMEENGIGEED ERTQGIKLLKTILKWLMASAGRSFS TAVTEQLQLLPLFFKIAPVE NDNSYDELKRDAKLCLSLMSQGLLY PHQVPLVLQVLKQTARSSSWHARYT VLTYLQTMVFYNLFIFLNNE DAVKDIRWLVISLLEDEQLEVREMA ATTLSGLLQCNFLTMDSPMQIHFEQ LCKTKLPKKRKRDPGSVGDT IPSAELVKRHAGVLGLGACVLSSPY DVPTWMPQLLMNLSAHLNDPQPIEM TVKKTLSNFRRTHHDNWQEH
  KQQFTDDQLLVLTDLLVSPCYYATR TRPLEQKLISEEDLAANDILDYKDD DDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Pathways: Proteasome

Gene Information

• Gene Name: PSME4 proteasome activator subunit 4 [ Homo sapiens (human) ]
• Official Symbol: PSME4
• Synonyms: PA200
• Gene ID: 23198
• mRNA Refseq: NM_014614.3
• Protein Refseq: NP_055429.2
• MIM: 607705
• UniProt ID: Q14997