| Description : |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. |
| Source : |
In Vitro Cell Free System |
| Species : |
Human |
| Form : |
Liquid |
| Molecular Mass : |
81.070kDa inclusive of tags |
| Protein Length : |
500 amino acids |
| AA Sequence : |
MAWAALLGLLAALLLLLLLSRRRTRRPGEPPLDLGSIPWL GYALDFGKDAASFLTRMKEKHGDIFTILVGGRYVTVLLDP HSYDAVVWEPRTRLDFHAYAIFLMERIFDVQLPHYSPSDE KARMKLTLLHRELQALTEAMYTNLHAVLLGDATEAGSGWH EMGLLDFSYSFLLRAGYLTLYGIEALPRTHESQAQDRVHS ADVFHTFRQLDRLLPKLARGSLSVGDKDHMCSVKSRLWKL LSPARLARRAHRSKWLESYLLHLEEMGVSEEMQARALVLQ LWATQGNMGPAAFWLLLFLLKNPEALAAVRGELESILWQA EQPVSQTTTLPQKVLDSTPVLDSVLSESLRLTAAPFITRE VVVDLAMPMADGREFNLRRGDRLLLFPFLSPQRDPEIYTD PEVFKYNRFLNPDGSEKKDFYKDGKRLKNYNMPWGAGHNH CLGRSYAVNSIKQFVFLVLVHLDLELINADVEIPEFDLSR YGFGLMQPEHDVPVRYRIRP |
| Purity : |
Proprietary Purification |
| Storage : |
Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles. |
| Storage Buffer : |
pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione. |
