Recombinant Full Length Human RAC1 Protein, C-Flag-tagged
Cat.No. : | RAC1-1105HFL |
Product Overview : | Recombinant Full Length Human RAC1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
- Download
Description : | The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 21.3 kDa |
AA Sequence : | MQAIKCVVVGDGAVGKTCLLISYTT NAFPGEYIPTVFDNYSANVMVDGKP VNLGLWDTAGQEDYDRLRPL SYPQTDVFLICFSLVSPASFENVRA KWYPEVRHHCPNTPIILVGTKLDLR DDKDTIEKLKEKKLTPITYP QGLAMAKEIGAVKYLECSALTQRGL KTVFDEAIRAVLCPPPVKKRKRKCL LLTRTRPLEQKLISEEDLAANDILD YKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome |
Protein Pathways : | Adherens junction, Amyotrophic lateral sclerosis (ALS), Axon guidance, B cell receptor signaling pathway, Chemokine signaling pathway, Colorectal cancer, Epithelial cell signaling in Helicobacter pylori infection, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, Leukocyte transendothelial migration, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Pancreatic cancer, Pathways in cancer, Regulation of actin cytoskeleton, Renal cell carcinoma, Toll-like receptor signaling pathway, VEGF signaling pathway, Viral myocarditis, Wnt signaling pathway |
Gene Name : | RAC1 Rac family small GTPase 1 [ Homo sapiens (human) ] |
Official Symbol : | RAC1 |
Synonyms : | MIG5; MRD48; Rac-1; TC-25; p21-Rac1 |
Gene ID : | 5879 |
mRNA Refseq : | NM_006908.5 |
Protein Refseq : | NP_008839.2 |
MIM : | 602048 |
UniProt ID : | P63000 |
Products Types
◆ Recombinant Protein | ||
RAC1-7379M | Recombinant Mouse RAC1 Protein, His (Fc)-Avi-tagged | +Inquiry |
RAC1-445H | Recombinant Human RAC1 Protein, MYC/DDK-tagged | +Inquiry |
RAC1-4567R | Recombinant Rat RAC1 Protein, His (Fc)-Avi-tagged | +Inquiry |
RAC1-1845H | Recombinant Human RAC1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Rac1-5344M | Recombinant Mouse Rac1 Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
RAC1-712HCL | Recombinant Human RAC1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (5)
Ask a questionYes, there are clinical trials investigating the efficacy of RAC1-targeted therapies in various diseases, including cancer and inflammatory disorders.
RAC1 activation is implicated in the development of diabetic complications, particularly in the context of vascular dysfunction and diabetic nephropathy.
Research suggests that altered RAC1 expression and activity may serve as a biomarker for certain neurodegenerative diseases.
RAC1 is crucial for neurite outgrowth and synaptic plasticity, and its dysregulation has been implicated in neurological disorders, suggesting a potential target for therapeutic interventions.
RAC1 is involved in vascular smooth muscle cell migration, and its dysregulation is associated with cardiovascular diseases. Targeting RAC1 may offer therapeutic benefits in such cases.
Customer Reviews (3)
Write a reviewRAC1 protein is highly recommended for researchers and scientists due to its exceptional performance in ELISA assays.
Its reliability in ELISA makes it a trusted tool for quantitative and qualitative protein analysis.
With its superior binding affinity and specificity, RAC1 protein enables accurate and reliable detection of target analytes in various biological samples.
Ask a Question for All RAC1 Products
Required fields are marked with *
My Review for All RAC1 Products
Required fields are marked with *
Inquiry Basket