Recombinant Full Length Human RIPK2 Protein, GST-tagged
Cat.No. : | RIPK2-6795HF |
Product Overview : | Recombinant full-length Human RIPK2 Protein (1-540 a.a.) is produced by Wheat Germ (in vitro) expression system. This protein is fused with a GST tag at the N-terminal. |
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Description : | This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli. |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Form : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Molecular Mass : | 87.6 kDa |
Protein Length : | 540 amino acids |
AA Sequence : | MNGEAICSALPTIPYHKLADLRYLS RGASGTVSSARHADWRVQVAVKHLH IHTPLLDSERKDVLREAEILHKARF SYILPILGICNEPEFLGIVTEYMPN GSLNELLHRKTEYPDVAWPLRFRIL HEIALGVNYLHNMTPPLLHHDLKTQ NILLDNEFHVKIADFGLSKWRMMSL SQSRSSKSAPEGGTIIYMPPENYEP GQKSRASIKHDIYSYAVITWEVLSR KQPFEDVTNPLQIMYSVSQGHRPVI NEESLPYDIPHRARMISLIESGWAQ NPDERPSFLKCLIELEPVLRTFEEI TFLEAVIQLKKTKLQSVSSAIHLCD KKKMELSLNIPVNHGPQEESCGSSQ LHENSGSPETSRSLPAPQDNDFLSR KAQDCYFMKLHHCPGNHSWDSTISG SQRAAFCDHKTTPCSSAIINPLSTA GNSERLQPGIAQQWIQSKREDIVNQ MTEACLNQSLDALLSRDLIMKEDYE LVSTKPTRTSKVRQLLDTTDIQGEE FAKVIVQKLKDNKQMGLQPYPEILV VSRSPSLNLLQNKSM |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Gene Name : | RIPK2 receptor-interacting serine-threonine kinase 2 [ Homo sapiens ] |
Official Symbol : | RIPK2 |
Synonyms : | RIPK2; CARD3; CARDIAK; RICK; RIP2; RIP-2; CCK; GIG30; |
Gene ID : | 8767 |
mRNA Refseq : | NM_003821 |
Protein Refseq : | NP_003812 |
MIM : | 603455 |
UniProt ID : | O43353 |
Products Types
◆ Recombinant Protein | ||
RIPK2-5565H | Recombinant Human RIPK2, GST-tagged | +Inquiry |
Ripk2-5522M | Recombinant Mouse Ripk2 Protein, Myc/DDK-tagged | +Inquiry |
RIPK2-5564H | Recombinant Human RIPK2 Protein, His-tagged | +Inquiry |
RIPK2-7616M | Recombinant Mouse RIPK2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Ripk2-1795M | Recombinant Mouse Ripk2 protein, His & T7-tagged | +Inquiry |
◆ Lysates | ||
RIPK2-2333HCL | Recombinant Human RIPK2 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-1623 | RIPK2 Kinase Binding Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionRIPK2 plays a significant role in driving inflammatory responses, implicated in autoimmune disease mechanisms.
RIPK2 is crucial in NOD1/NOD2 signaling, activating innate immune responses against microbial intrusions.
Changes in RIPK2 signaling can impact cancer development, influencing tumor cell survival and immune interactions.
RIPK2 regulates NF-κB activation and cytokine production, crucial for immune response and inflammation.
RIPK2 modulates defense mechanisms against bacterial pathogens, coordinating immune signaling and responses.
RIPK2 influences cell survival and apoptosis decisions, particularly in response to stress or microbial infection.
Dysregulation of RIPK2 is linked to IBD, affecting intestinal inflammation and immune responses.
Customer Reviews (3)
Write a reviewPrecise mass spectrometry analysis, key for our proteomics investigations.
Dependable protein purification, consistently delivers high yield and purity.
Great antibody validation, enhances our immunoprecipitation success.
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