Recombinant Full Length Human SAMHD1 Protein, C-Flag-tagged

• Cat.No.: SAMHD1-486HFL
• Product Overview: Recombinant Full Length Human SAMHD1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 72 kDa
• AA Sequence: MQRADSEQPSKRPRCDDSPRTPSNT PSAEADWSPGLELHPDYKTWGPEQV CSFLRRGGFEEPVLLKNIRE NEITGALLPCLDESRFENLGVSSLG ERKKLLSYIQRLVQIHVDTMKVIND PIHGHIELHPLLVRIIDTPQ FQRLRYIKQLGGGYYVFPGASHNRF EHSLGVGYLAGCLVHALGEKQPELQ ISERDVLCVQIAGLCHDLGH GPFSHMFDGRFIPLARPEVKWTHEQ GSVMMFEHLINSNGIKPVMEQYGLI PEEDICFIKEQIVGPLESPV EDSLWPYKGRPENKSFLYEIVSNKR NGIDVDKWDYFARDCHHLGIQNNFD YKRFIKFARVCEVDNELRIC ARDKEVGNLYDMFHTRNSLHRRAYQ HKVGNIIDTMITDAFLKADDYIEIT GAGEKKYRISTAIDDMEAYT KLTDNIFLEILYSTDPKLKDAREIL KQIEYRNLFKYVGETQPTGQIKIKR EDYESLPKEVASAKPKVLLD VKLKAEDFIVDVINMDYGMQEKNPI DHVSFYCKTAPNRAIRITKNQVSQL LPEKFVEQLIRVYCKKVDRK SLYAARQYFVQWCADRNFTKPQDGD VIAPLITPQKKEWNDSTSVQNPTRL REASKSRVQLFKDDPMTRTRPLEQK LISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: SAMHD1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 [ Homo sapiens (human) ]
• Official Symbol: SAMHD1
• Synonyms: DCIP; CHBL2; HDDC1; MOP-5; SBBI88; hSAMHD1
• Gene ID: 25939
• mRNA Refseq: NM_015474.4
• Protein Refseq: NP_056289.2
• MIM: 606754
• UniProt ID: Q9Y3Z3