Recombinant Full Length Human SF3A1 Protein, C-Flag-tagged

• Cat.No.: SF3A1-1620HFL
• Product Overview: Recombinant Full Length Human SF3A1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a subunit of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer is a component of the mature U2 small nuclear ribonucleoprotein particle (snRNP). U2 small nuclear ribonucleoproteins play a critical role in spliceosome assembly and pre-mRNA splicing.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 88.7 kDa
• AA Sequence: MPAGPVQAVPPPPPVPTEPKQPTEE EASSKEDSAPSKPVVGIIYPPPEVR NIVDKTASFVARNGPEFEAR IRQNEINNPKFNFLNPNDPYHAYYR HKVSEFKEGKAQEPSAAIPKVMQQQ QQTTQQQLPQKVQAQVIQET IVPKEPPPEFEFIADPPSISAFDLD VVKLTAQFVARNGRQFLTQLMQKEQ RNYQFDFLRPQHSLFNYFTK LVEQYTKILIPPKGLFSKLKKEAEN PREVLDQVCYRVEWAKFQERERKKE EEEKEKERVAYAQIDWHDFV VVETVDFQPNEQGNFPPPTTPEELG ARILIQERYEKFGESEEVEMEVESD EEDDKQEKAEEPPSQLDQDT QVQDMDEGSDDEEEGQKVPPPPETP MPPPLPPTPDQVIVRKDYDPKASKP LPPAPAPDEYLVSPITGEKI PASKMQEHMRIGLLDPRWLEQRDRS IREKQSDDEVYAPGLDIESSLKQLA ERRTDIFGVEETAIGKKIGE EEIQKPEEKVTWDGHSGSMARTQQA AQANITLQEQIEAIHKAKGLVPEDD TKEKIGPSKPNEIPQQPPPP SSATNIPSSAPPITSVPRPPTMPPP VRTTVVSAVPVMPRPPMASVVRLPP GSVIAPMPPIIHAPRINVVP MPPSAPPIMAPRPPPMIVPTAFVPA PPVAPVPAPAPMPPVHPPPPMEDEP TSKKLKTEDSLMPEEEFLRR NKGPVSIKVQVPNMQDKTEWKLNGQ VLVFTLPLTDQVSVIKVKIHEATGM PAGKQKLQYEGIFIKDSNSL
  AYYNMANGAVIHLALKERGGRKKTR TRPLEQKLISEEDLAANDILDYKDD DDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome
• Protein Pathways: Spliceosome

Gene Information

• Gene Name: SF3A1 splicing factor 3a subunit 1 [ Homo sapiens (human) ]
• Official Symbol: SF3A1
• Synonyms: PRP21; PRPF21; SAP114; SF3A120
• Gene ID: 10291
• mRNA Refseq: NM_005877.6
• Protein Refseq: NP_005868.1
• MIM: 605595
• UniProt ID: Q15459