Recombinant Full Length Human SH2B3 Protein, C-Flag-tagged
Cat.No. : | SH2B3-812HFL |
Product Overview : | Recombinant Full Length Human SH2B3 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 63 kDa |
AA Sequence : | MNGPALQPSSPSSAPSASPAAAPRG WSEFCELHAVAAARELARQYWLFAR EHPQHAPLRAELVSLQFTDL FQRYFCREVRDGRAPGRDYRDTGRG PPAKAEASPEPGPGPAAPGLPKARS SEELAPPRPPGPCSFQHFRR SLRHIFRRRSAGELPAAHTAAAPGT PGEAAETPARPGLAKKFLPWSLARE PPPEALKEAVLRYSLADEAS MDSGARWQRGRLALRRAPGPDGPDR VLELFDPPKSSRPKLQAACSSIQEV RRCTRLEMPDNLYTFVLKVK DRTDIIFEVGDEQQLNSWMAELSEC TGRGLESTEAEMHIPSALEPSTSSS PRGSTDSLNQGASPGGLLDP ACQKTDHFLSCYPWFHGPISRVKAA QLVQLQGPDAHGVFLVRQSETRRGE YVLTFNFQGIAKHLRLSLTE RGQCRVQHLHFPSVVDMLHHFQRSP IPLECGAACDVRLSSYVVVVSQPPG SCNTVLFPFSLPHWDSESLP HWGSELGLPHLSSSGCPRGLSPEGL PGRSSPPEQIFHLVPSPEELANSLQ HLEHEPVNRARDSDYEMDSS SRSHLRAIDNQYTPLTRTRPLEQKL ISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Pathways : | Neurotrophin signaling pathway |
Gene Name : | SH2B3 SH2B adaptor protein 3 [ Homo sapiens (human) ] |
Official Symbol : | SH2B3 |
Synonyms : | LNK; IDDM20 |
Gene ID : | 10019 |
mRNA Refseq : | NM_005475.3 |
Protein Refseq : | NP_005466.1 |
MIM : | 605093 |
UniProt ID : | Q9UQQ2 |
Products Types
◆ Recombinant Protein | ||
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SH2B3-054H | Recombinant Human SH2B3 Mutant (R262W) Protein, DDK/His-tagged | +Inquiry |
SH2B3-051H | Recombinant Human SH2B3 Mutant (R262W) Protein, Myc/DDK-tagged | +Inquiry |
SH2B3-5032R | Recombinant Rat SH2B3 Protein, His (Fc)-Avi-tagged | +Inquiry |
SH2B3-8115M | Recombinant Mouse SH2B3 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
SH2B3-1880HCL | Recombinant Human SH2B3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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