Recombinant Full Length Human SNRPC Protein, C-Flag-tagged

• Cat.No.: SNRPC-1005HFL
• Product Overview: Recombinant Full Length Human SNRPC Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes one of the specific protein components of the U1 small nuclear ribonucleoprotein (snRNP) particle required for the formation of the spliceosome. The encoded protein participates in the processing of nuclear precursor messenger RNA splicing. snRNP particles are attacked by autoantibodies frequently produced by patients with connective tissue diseases. The genome contains several pseudogenes of this functional gene. Alternative splicing results in a non-coding transcript variant.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 17.2 kDa
• AA Sequence: MPKFYCDYCDTYLTHDSPSVRKTHC SGRKHKENVKDYYQKWMEEQAQSLI DKTTAAFQQGKIPPTPFSAP PPAGAMIPPPPSLPGPPRPGMMPAP HMGGPPMMPMMGPPPPGMMPVGPAP GMRPPMGGHMPMMPGPPMMR
  PPARPMMVPTRPGMTRPDRTRTRPL EQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Stem cell - Pluripotency
• Protein Pathways: Spliceosome

Gene Information

• Gene Name: SNRPC small nuclear ribonucleoprotein polypeptide C [ Homo sapiens (human) ]
• Official Symbol: SNRPC
• Synonyms: U1C; Yhc1
• Gene ID: 6631
• mRNA Refseq: NM_003093.3
• Protein Refseq: NP_003084.1
• MIM: 603522
• UniProt ID: P09234