Recombinant Full Length Human SOX2 Protein, C-Flag-tagged

• Cat.No.: SOX2-1613HFL
• Product Overview: Recombinant Full Length Human SOX2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 34.1 kDa
• AA Sequence: MYNMMETELKPPGPQQTSGGGGGNS TAAAAGGNQKNSPDRVKRPMNAFMV WSRGQRRKMAQENPKMHNSE ISKRLGAEWKLLSETEKRPFIDEAK RLRALHMKEHPDYKYRPRRKTKTLM KKDKYTLPGGLLAPGGNSMA SGVGVGAGLGAGVNQRMDSYAHMNG WSNGSYSMMQDQLGYPQHPGLNAHG AAQMQPMHRYDVSALQYNSM TSSQTYMNGSPTYSMSYSQQGTPGM ALGSMGSVVKSEASSSPPVVTSSSH SRAPCQAGDLRDMISMYLPG
  AEVPEPAAPSRLHMSQHYQSGPVPG TAINGTLPLSHMTRTRPLEQKLISE EDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Adult stem cells, Cancer stem cells, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors

Gene Information

• Gene Name: SOX2 SRY-box transcription factor 2 [ Homo sapiens (human) ]
• Official Symbol: SOX2
• Synonyms: ANOP3; MCOPS3
• Gene ID: 6657
• mRNA Refseq: NM_003106.4
• Protein Refseq: NP_003097.1
• MIM: 184429
• UniProt ID: P48431