Recombinant Full Length Human STAB2 Protein, C-Flag-tagged

• Cat.No.: STAB2-1519HFL
• Product Overview: Recombinant Full Length Human STAB2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and lysosomes.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 274.7 kDa
• AA Sequence: MMLQHLVIFCLGLVVQNFCSPAETT GQARRCDRKSLLTIRTECRSCALNL GVKCPDGYTMITSGSVGVRD CRYTFEVRTYSLSLPGCRHICRKDY LQPRCCPGRWGPDCIECPGGAGSPC NGRGSCAEGMEGNGTCSCQE GFGGTACETCADDNLFGPSCSSVCN CVHGVCNSGLDGDGTCECYSAYTGP KCDKPIPECAALLCPENSRC SPSTEDENKLECKCLPNYRGDGKYC DPINPCLRKICHPHAHCTYLGPNRH SCTCQEGYRGDGQVCLPVDP CQINFGNCPTKSTVCKYDGPGQSHC ECKEHYQNFVPGVGCSMTDICKSDN PCHRNANCTTVAPGRTECIC QKGYVGDGLTCYGNIMERLRELNTE PRGKWQGRLTSFISLLDKAYAWPLS KLGPFTVLLPTDKGLKGFNV NELLVDNKAAQYFVKLHIIAGQMNI EYMNNTDMFYTLTGKSGEIFNSDKD NQIKLKLHGGKKKVKIIQGD IIASNGLLHILDRAMDKLEPTFESN NEQTIMTMLQPRYSKFRSLLEETNL GHALDEDGVGGPYTIFVPNN EALNNMKDGTLDYLLSPEGSRKLLE LVRYHIVPFTQLEVATLISTPHIRS MANQLIQFNTTDNGQILAND VAMEEIEITAKNGRIYTLTGVLIPP SIVPILPHRCDETKREMKLGTCVSC SLVYWSRCPANSEPTALFTH RCVYSGRFGSLKSGCARYCNATVKI PKCCKGFYGPDCNQCPGGFSNPCSG NGQCADSLGGNGTCICEEGF QGSQCQFCSDPNKYGPRCNKKCLCV HGTCNNRIDSDGACLTGTCRDGSAG RLCDKQTSACGPYVQFCHIH ATCEYSNGTASCICKAGYEGDGTLC SEMDPCTGLTPGGCSRNAECIKTGT GTHTCVCQQGWTGNGRDCSE INNCLLPSAGGCHDNASCLYVGPGQ NECECKKGFRGNGIDCEPITSCLEQ TGKCHPLASCQSTSSGVWSC VCQEGYEGDGFLCYGNAAVELSFLS EAAIFNRWINNASLQPTLSATSNLT VLVPSQQATEDMDQDEKSFW LSQSNIPALIKYHMLLGTYRVADLQ TLSSSDMLATSLQGNFLHLAKVDGN ITIEGASIVDGDNAATNGVI HIINKVLVPQRRLTGSLPNLLMRLE QMPDYSIFRGYIIQYNLANAIEAAD AYTVFAPNNNAIENYIREKK VLSLEEDVLRYHVVLEEKLLKNDLH NGMHRETMLGFSYFLSFFLHNDQLY VNEAPINYTNVATDKGVIHG LGKVLEIQKNRCDNNDTTIIRGRCR TCSSELTCPFGTKSLGNEKRRCIYT SYFMGRRTLFIGCQPKCVRT VITRECCAGFFGPQCQPCPGNAQNV CFGNGICLDGVNGTGVCECGEGFSG TACETCTEGKYGIHCDQACS CVHGRCNQGPLGDGSCDCDVGWRGV HCDNATTEDNCNGTCHTSANCLTNS DGTASCKCAAGFQGNGTICT AINACEISNGGCSAKADCKRTTPGR RVCTCKAGYTGDGIVCLEINPCLEN HGGCDKNAECTQTGPNQAAC NCLPAYTGDGKVCTLINVCLTKNGG CSEFAICNHTGQVERTCTCKPNYIG DGFTCRGSIYQELPKNPKTS QYFFQLQEHFVKDLVGPGPFTVFAP LSAAFDEEARVKDWDKYGLMPQVLR YHVVACHQLLLENLKLISNA TSLQGEPIVISVSQSTVYINNKAKI ISSDIISTNGIVHIIDKLLSPKNLL ITPKDNSGRILQNLTTLATN NGYIKFSNLIQDSGLLSVITDPIHT PVTLFWPTDQALHALPAEQQDFLFN QDNKDKLKEYLKFHVIRDAK VLAVDLPTSTAWKTLQGSELSVKCG AGRDIGDLFLNGQTCRIVQRELLFD LGVAYGIDCLLIDPTLGGRC DTFTTFDASGECGSCVNTPSCPRWS KPKGVKQKCLYNLPFKRNLEGCRER CSLVIQIPRCCKGYFGRDCQ ACPGGPDAPCNNRGVCLDQYSATGE CKCNTGFNGTACEMCWPGRFGPDCL PCGCSDHGQCDDGITGSGQC LCETGWTGPSCDTQAVLPAVCTPPC SAHATCKENNTCECNLDYEGDGITC TVVDFCKQDNGGCAKVARCS QKGTKVSCSCQKGYKGDGHSCTEID PCADGLNGGCHEHATCKMTGPGKHK CECKSHYVGDGLNCEPEQLP IDRCLQDNGQCHADAKCVDLHFQDT TVGVFHLRSPLGQYKLTFDKAREAC ANEAATMATYNQLSYAQKAK YHLCSAGWLETGRVAYPTAFASQNC GSGVVGIVDYGPRPNKSEMWDVFCY RMKDVNCTCKVGYVGDGFSC SGNLLQVLMSFPSLTNFLTEVLAYS NSSARGRAFLEHLTDLSIRGTLFVP QNSGLGENETLSGRDIEHHL ANVSMFFYNDLVNGTTLQTRLGSKL LITASQDPLQPTETRFVDGRAILQW DIFASNGIIHVISRPLKAPP APVTLTHTGLGAGIFFAIILVTGAV ALAAYSYFRINRRTIGFQHFESEED INVAALGKQQPENISNPLYE
  STTSAPPEPSYDPFTDSEERQLEGN DPLRTLTRTRPLEQKLISEEDLAAN DILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Transmembrane

Gene Information

• Gene Name: STAB2 stabilin 2 [ Homo sapiens (human) ]
• Official Symbol: STAB2
• Synonyms: FEX2; HARE; FEEL2; FELL2; FELE-2; SCARH1
• Gene ID: 55576
• mRNA Refseq: NM_017564.10
• Protein Refseq: NP_060034.9
• MIM: 608561
• UniProt ID: Q8WWQ8