Recombinant Full Length Human STAR Protein, C-Flag-tagged

• Cat.No.: STAR-1693HFL
• Product Overview: Recombinant Full Length Human STAR Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 31.7 kDa
• AA Sequence: MLLATFKLCAGSSYRHMRNMKGLRQ QAVMAISQELNRRALGGPTPSTWIN QVRRRSSLLGSRLEETLYSD QELAYLQQGEEAMQKALGILSNQEG WKKESQQDNGDKVMSKVVPDVGKVF RLEVVVDQPMERLYEELVER MEAMGEWNPNVKEIKVLQKIGKDTF ITHELAAEAAGNLVGPRDFVSVRCA KRRGSTCVLAGMATDFGNMP EQKGVIRAEHGPTCMVLHPLAGSPS KTKLTWLLSIDLKGWLPKSIINQVL SQTQVDFANHLRKRLESHPA
  SEARCTRTRPLEQKLISEEDLAAND ILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome

Gene Information

• Gene Name: STAR steroidogenic acute regulatory protein [ Homo sapiens (human) ]
• Official Symbol: STAR
• Synonyms: STARD1
• Gene ID: 6770
• mRNA Refseq: NM_000349.3
• Protein Refseq: NP_000340.2
• MIM: 600617
• UniProt ID: P49675