Recombinant Full Length Human STXBP1 Protein, C-Flag-tagged

• Cat.No.: STXBP1-457HFL
• Product Overview: Recombinant Full Length Human STXBP1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor. Mutations in this gene have been associated with infantile epileptic encephalopathy-4. Alternatively spliced transcript variants have been described.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 68.6 kDa
• AA Sequence: MAPIGLKAVVGEKIMHDVIKKVKKK GEWKVLVVDQLSMRMLSSCCKMTDI MTEGITIVEDINKRREPLPS LEAVYLITPSEKSVHSLISDFKDPP TAKYRAAHVFFTDSCPDALFNELVK SRAAKVIKTLTEINIAFLPY ESQVYSLDSADSFQSFYSPHKAQMK NPILERLAEQIATLCATLKEYPAVR YRGEYKDNALLAQLIQDKLD AYKADDPTMGEGPDKARSQLLILDR GFDPSSPVLHELTFQAMSYDLLPIE NDVYKYETSGIGEARVKEVL LDEDDDLWIALRHKHIAEVSQEVTR SLKDFSSSKRMNTGEKTTMRDLSQM LKKMPQYQKELSKYSTHLHL AEDCMKHYQGTVDKLCRVEQDLAMG TDAEGEKIKDPMRAIVPILLDANVS TYDKIRIILLYIFLKNGITE ENLNKLIQHAQIPPEDSEIITNMAH LGVPIVTDSTLRRRSKPERKERISE QTYQLSRWTPIIKDIMEDTI EDKLDTKHYPYISTRSSASFSTTAV SARYGHWHKNKAPGEYRSGPRLIIF ILGGVSLNEMRCAYEVTQAN
  GKWEVLIGSTHILTPTKFLMDLRHP DFRESSRVSFEDQAPTMETRTRPLE QKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: STXBP1 syntaxin binding protein 1 [ Homo sapiens (human) ]
• Official Symbol: STXBP1
• Synonyms: P67; DEE4; NSEC1; UNC18; N-Sec1; RBSEC1; unc-18A; unc18-1; MUNC18-1
• Gene ID: 6812
• mRNA Refseq: NM_003165.6
• Protein Refseq: NP_003156.1
• MIM: 602926
• UniProt ID: P61764