Recombinant Full Length Human TCF3 Protein, C-Flag-tagged
Cat.No. : | TCF3-1948HFL |
Product Overview : | Recombinant Full Length Human TCF3 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19), with PBX1), childhood leukemia (t(19;19), with TFPT) and acute leukemia (t(12;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 67.1 kDa |
AA Sequence : | MNQPQRMAPVGTDKELSDLLDFSMM FPLPVTNGKGRPASLAGAQFGGSGL EDRPSSGSWGSGDQSSSSFD PSRTFSEGTHFTESHSSLSSSTFLG PGLGGKSGERGAYASFGRDAGVGGL TQAGFLSGELALNSPGPLSP SGMKGTSQYYPSYSGSSRRRAADGS LDTQPKKVRKVPPGLPSSVYPPSSG EDYGRDATAYPSAKTPSSTY PAPFYVADGSLHPSAELWSPPGQAG FGPMLGGGSSPLPLPPGSGPVGSSG SSSTFGGLHQHERMGYQLHG AEVNGGLPSASSFSSAPGATYGGVS SHTPPVSGADSLLGSRGTTAGSSGD ALGKALASIYSPDHSSNNFS SSPSTPVGSPQGLAGTSQWPRAGAP GALSPSYDGGLHGLQSKIEDHLDEA IHVLRSHAVGTAGDMHTLLP GHGALASGFTGPMSLGGRHAGLVGG SHPEDGLAGSTSLMHNHAALPSQPG TLPDLSRPPDSYSGLGRAGA TAAASEIKREEKEDEENTSAADHSE EEKKELKAPRARTSSTDEVLSLEEK DLRDRERRMANNARERVRVR DINEAFRELGRMCQMHLKSDKAQTK LLILQQAVQVILGLEQQVRERNLNP KAACLKRREEEKVSGVVGDP QMVLSAPHPGLSEAHNPAGHM TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors |
Gene Name : | TCF3 transcription factor 3 [ Homo sapiens (human) ] |
Official Symbol : | TCF3 |
Synonyms : | E2A; E47; p75; AGM8; ITF1; VDIR; AGM8A; AGM8B; TCF-3; bHLHb21 |
Gene ID : | 6929 |
mRNA Refseq : | NM_001136139.4 |
Protein Refseq : | NP_001129611.1 |
MIM : | 147141 |
UniProt ID : | P15923 |
Products Types
◆ Recombinant Protein | ||
Tcf3-2118M | Recombinant Mouse Tcf3 Protein, His-tagged | +Inquiry |
Tcf3-6339M | Recombinant Mouse Tcf3 Protein, Myc/DDK-tagged | +Inquiry |
TCF3-5648R | Recombinant Rat TCF3 Protein, His (Fc)-Avi-tagged | +Inquiry |
TCF3-2167H | Recombinant Human TCF3 Protein, His (Fc)-Avi-tagged | +Inquiry |
TCF3-29462TH | Recombinant Human TCF3 | +Inquiry |
◆ Lysates | ||
TCF3-1180HCL | Recombinant Human TCF3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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