Recombinant Full Length Human TDRD6 Protein, C-Flag-tagged

• Cat.No.: TDRD6-571HFL
• Product Overview: Recombinant Full Length Human TDRD6 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a tudor domain-containing protein and component of the chromatoid body, a type of ribonucleoprotein granule present in male germ cells. Studies in rodents have demonstrated a role for the encoded protein in spermiogenesis and the nonsense mediated decay (NMD) pathway. This protein is a major autoantigen in human patients with autoimmune polyendocrine syndrome type 1 (APS1).
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 236.3 kDa
• AA Sequence: MCSTPGMPAPGASLALRVSFVDVHP DVIPVQLWGLVGERRGEYLRLSREI QEAAATRGQWALGSASASPG ELCLVQVGLLWHRCRVVSRQAQESR VFLLDEGRTITAGAGSLAPGRREFF NLPSEVLGCVLAGLVPAGCG AGSGEPPQHWPADAVDFLSNLQGKE VHGCVLDVLLLHRLVLLEVPDVFQQ MRELGLARRVPDSLFRSLLE RYLTAATASVGSGVPVLSRVPLKQK QPGLDYFYPQLQLGVTEAVVITQVC HPHRIHCQLRSVSQEIHRLS ESMAQVYRGSTGTGDENSTSATWEE REESPDKPGSPCASCGLDGHWYRAL LLETFRPQRCAQVLHVDYGR KELVSCSSLRYLLPEYFRMPVVTYP CALYGLWDGGRGWSRSQVGDLKTLI LGKAVNAKIEFYCSFEHVYY VSLYGEDGINLNRVFGVQSCCLADR VLQSQATEEEEPETSQSQSPAEEVD EEISLPALRSIRLKMNAFYD AQVEFVKNPSEFWIRLRKHNVTFSK LMRRMCGFYSSASKLDGVVLKPEPD DLCCVKWKENGYYRAIVTKL DDKSVDVFLVDRGNSENVDWYDVRM LLPQFRQLPILAVKCTLADIWPLGK TWSQEAVSFFKKTVLHKELV IHILDKQDHQYVIEILDESRTGEEN ISKVIAQAGYAKYQEFETKENILVN AHSPGHVSNHFTTESNKIPF AKTGEGEQKAKRENKTTSVSKALSD TTVVTNGSTELVVQEKVKRASVYFP LMQNCLEIKPGSSSKGELEV GSTVEVRVSYVENPGYFWCQLTRNI QGLKTLMSDIQYYCKNTAAPHQRNT LACLAKRTVNRQWSRALISG IQSVEHVNVTFVDYGDREMVSVKNI YSISEEFLKVKAQAFRCSLYNLIQP VGQNPFVWDVKAIQAFNEFI DNAWQKNLELKCTIFALASINEELF NIVDLLTPFQSACHFLVEKRLARPV KLQKPLESSVQLHSYFYSTH DMKIGSEELVYITHIDDPWTFYCQL ARNANILEQLSCSITQLSKVLLNLK TSPLNPGTLCLAKYTDGNWY RGIVIEKEPKKVFFVDFGNIYVVTS DDLLPIPSDAYDVLLLPMQAVRCSL SDIPDHIPEEVVVWFQETIL DKSLKALVVAKDPDGTLIIELYGDN IQISASINKKLGLLSYKDRIRKKES EVLCSTTETLEEKNENMKLP CTEYLSKSVGYKLPNKEILEESYKP QINSSYKELKLLQSLTKTNLVTQYQ DSVGNKNSQVFPLTTEKKEE ISAETPLKTARVEATLSERKIGDSC DKDLPLKFCEFPQKTIMPGFKTTVY VSHINDLSDFYVQLIEDEAE ISHLSERLNSVKTRPEYYVGPPLQR GDMICAVFPEDNLWYRAVIKEQQPN DLLSVQFIDYGNVSVVHTNK IGRLDLVNAILPGLCIHCSLQGFEV PDNKNSKKMMHYFSQRTSEAAIRCE FVKFQDRWEVILADEHGIIA DDMISRYALSEKSQVELSTQVIKSA SSKSVNKSDIDTSVFLNWYNPEKKM IRAYATVIDGPEYFWCQFAD TEKLQCLEVEVQTAGEQVADRRNCI PCPYIGDPCIVRYREDGHYYRALIT NICEDYLVSVRLVDFGNIED CVDPKALWAIPSELLSVPMQAFPCC LSGFNISEGLCSQEGNDYFYEIITE DVLEITILEIRRDVCDIPLA IVDLKSKGKSINEKMEKYSKTGIKS ALPYENIDSEIKQTLGSYNLDVGLK KLSNKAVQNKIYMEQQTDEL AEITEKDVNIIGTKPSNFRDPKTDN ICEGFENPCKDKIDTEELEGELECH LVDKAEFDDKYLITGFNTLL PHANETKEILELNSLEVPLSPDDES KEFLELESIELQNSLVVDEEKGELS PVPPNVPLSQECVTKGAMEL FTLQLPLSCEAEKQPELELPTAQLP LDDKMDPLSLGVSQKAQESMCTEDM RKSSCVESFDDQRRMSLHLH GADCDPKTQNEMNICEEEFVEYKNR DAISALMPLFSEEESSDGSKHNNGL PDHISAQLQNTYTLKAFTVG SKCVVWSSLRNTWSKCEILETAEEG TRVLNLSNGMEEIVNPENVWNGIPK LDKSPPEKRGLEVMEITRTRPLEQK LISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: TDRD6 tudor domain containing 6 [ Homo sapiens (human) ]
• Official Symbol: TDRD6
• Synonyms: TDR2; CT41.2; SPATA36; NY-CO-45; bA446F17.4
• Gene ID: 221400
• mRNA Refseq: NM_001010870.3
• Protein Refseq: NP_001010870.1
• MIM: 611200
• UniProt ID: O60522