Recombinant Full Length Human TF Protein, C-Flag-tagged

• Cat.No.: TF-393HFL
• Product Overview: Recombinant Full Length Human TF Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 75.1 kDa
• AA Sequence: MRLAVGALLVCAVLGLCLAVPDKTV RWCAVSEHEATKCQSFRDHMKSVIP SDGPSVACVKKASYLDCIRA IAANEADAVTLDAGLVYDAYLAPNN LKPVVAEFYGSKEDPQTFYYAVAVV KKDSGFQMNQLRGKKSCHTG LGRSAGWNIPIGLLYCDLPEPRKPL EKAVANFFSGSCAPCADGTDFPQLC QLCPGCGCSTLNQYFGYSGA FKCLKNGAGDVAFVKHSTIFENLAN KADRDQYELLCLDNTRKPVDEYKDC HLAQVPSHTVVARSMGGKED LIWELLNQAQEHFGKDKSKEFQLFS SPHGKDLLFKDSAHGFLKVPPRMDA KMYLGYEYVTAIRNLREGTC QEAPTDECKPVKWCALSHHERLKCD EWSVNSVGKIECVSAETTEDCIAKI MNGEADAMSLDGGFVYIAGK CGLVPVLAENYNKSDNCEDTPEAGY FAVAVVKKSASDLTWDNLKGKKSCH TAVGRTAGWNIPMGLLYNKI NHCRFDEFFSEGCAPGSKKDSSLCK LCMGSGLNLCEPNNKEGYYGYTGAF RCLVEKGDVAFVKHQTVPQN TGGKNPDPWAKNLNEKDYELLCLDG TRKPVEEYANCHLARAPNHAVVTRK DKEACVHKILRQQQHLFGSN VTDCSGNFCLFRSETKDLLFRDDTV CLAKLHDRNTYEKYLGEEYVKAVGN LRKCSTSSLLEACTFRRPTRTRPLE QKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Secreted Protein

Gene Information

• Gene Name: TF transferrin [ Homo sapiens (human) ]
• Official Symbol: TF
• Synonyms: TFQTL1; PRO1557; PRO2086; HEL-S-71p
• Gene ID: 7018
• mRNA Refseq: NM_001063.4
• Protein Refseq: NP_001054.2
• MIM: 190000
• UniProt ID: P02787