Recombinant Full Length Human TPP2 Protein, C-Flag-tagged

• Cat.No.: TPP2-1098HFL
• Product Overview: Recombinant Full Length Human TPP2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a mammalian peptidase that, at neutral pH, removes tripeptides from the N terminus of longer peptides. The protein has a specialized function that is essential for some MHC class I antigen presentation. The protein is a high molecular mass serine exopeptidase; the amino acid sequence surrounding the serine residue at the active site is similar to the peptidases of the subtilisin class rather than the trypsin class.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 138.2 kDa
• AA Sequence: MATAATEEPFPFHGLLPKKETGAAS FLCRYPEYDGRGVLIAVLDTGVDPG APGMQVTTDGKPKIVDIIDT TGSGDVNTATEVEPKDGEIVGLSGR VLKIPASWTNPSGKYHIGIKNGYDF YPKALKERIQKERKEKIWDP VHRVALAEACRKQEEFDVANNGSSQ ANKLIKEELQSQVELLNSFEKKYSD PGPVYDCLVWHDGEVWRACI DSNEDGDLSKSTVLRNYKEAQEYGS FGTAEMLNYSVNIYDDGNLLSIVTS GGAHGTHVASIAAGHFPEEP ERNGVAPGAQILSIKIGDTRLSTME TGTGLIRAMIEVINHKCDLVNYSYG EATHWPNSGRICEVINEAVW KHNIIYVSSAGNNGPCLSTVGCPGG TTSSVIGVGAYVSPDMMVAEYSLRE KLPANQYTWSSRGPSADGAL GVSISAPGGAIASVPNWTLRGTQLM NGTSMSSPNACGGIALILSGLKANN IDYTVHSVRRALENTAVKAD NIEVFAQGHGIIQVDKAYDYLVQNT SFANKLGFTVTVGNNRGIYLRDPVQ VAAPSDHGVGIEPVFPENTE NSEKISLQLHLALTSNSSWVQCPSH LELMNQCRHINIRVDPRGLREGLHY TEVCGYDIASPNAGPLFRVP ITAVIAAKVNESSHYDLAFTDVHFK PGQIRRHFIEVPEGATWAEVTVCSC SSEVSAKFVLHAVQLVKQRA YRSHEFYKFCSLPEKGTLTEAFPVL GGKAIEFCIARWWASLSDVNIDYTI SFHGIVCTAPQLNIHASEGI NRFDVQSSLKYEDLAPCITLKNWVQ TLRPVSAKTKPLGSRDVLPNNRQLY EMVLTYNFHQPKSGEVTPSC PLLCELLYESEFDSQLWIIFDQNKR QMGSGDAYPHQYSLKLEKGDYTIRL QIRHEQISDLERLKDLPFIV SHRLSNTLSLDIHENHSFALLGKKK SSNLTLPPKYNQPFFVTSLPDDKIP KGAGPGCYLAGSLTLSKTEL GKKADVIPVHYYLIPPPTKTKNGSK DKEKDSEKEKDLKEEFTEALRDLKI QWMTKLDSSDIYNELKETYP NYLPLYVARLHQLDAEKERMKRLNE IVDAANAVISHIDQTALAVYIAMKT DPRPDAATIKNDMDKQKSTL VDALCRKGCALADHLLHTQAQDGAI STDAEGKEEEGESPLDSLAETFWET TKWTDLFDNKVLTFAYKHAL
  VNKMYGRGLKFATKLVEEKPTKENW KNCIQLMKLLGWTHCASFTENWLPI MYPPDYCVFTRTRPLEQKLISEEDL AANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Protease

Gene Information

• Gene Name: TPP2 tripeptidyl peptidase 2 [ Homo sapiens (human) ]
• Official Symbol: TPP2
• Synonyms: IMD78; TPP-2; TPPII; TPP-II
• Gene ID: 7174
• mRNA Refseq: NM_003291.4
• Protein Refseq: NP_003282.2
• MIM: 190470
• UniProt ID: P29144