Recombinant Full Length Human UBAP1 Protein, C-Flag-tagged

• Cat.No.: UBAP1-1193HFL
• Product Overview: Recombinant Full Length Human UBAP1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene is a member of the UBA domain family, whose members include proteins having connections to ubiquitin and the ubiquitination pathway. The ubiquitin associated domain is thought to be a non-covalent ubiquitin binding domain consisting of a compact three helix bundle. This particular protein originates from a gene locus in a refined region on chromosome 9 undergoing loss of heterozygosity in nasopharyngeal carcinoma (NPC). Taking into account its cytogenetic location, this UBA domain family member is being studies as a putative target for mutation in nasopharyngeal carcinomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 54.9 kDa
• AA Sequence: MASKKLGADFHGTFSYLDDVPFKTG DKFKTPAKVGLPIGFSLPDCLQVVR EVQYDFSLEKKTIEWAEEIK KIEEAEREAECKIAEAEAKVNSKSG PEGDSKMSFSKTHSTATMPPPINPI LASLQHNSILTPTRVSSSAT KQKVLSPPHIKADFNLADFECEEDP FDNLELKTIDEKEELRNILVGTTGP IMAQLLDNNLPRGGSGSVLQ DEEVLASLERATLDFKPLHKPNGFI TLPQLGNCEKMSLSSKVSLPPIPAV SNIKSLSFPKLDSDDSNQKT AKLASTFHSTSCLRNGTFQNSLKPS TQSSASELNGHHTLGLSALNLDSGT EMPALTSSQMPSLSVLSVCT EESSPPNTGPTVTPPNFSVSQVPNM PSCPQAYSELQMLSPSERQCVETVV NMGYSYECVLRAMKKKGENI EQILDYLFAHGQLCEKGFDPLLVEE ALEMHQCSEEKMMEFLQLMSKFKEM GFELKDIKEVLLLHNNDQDN
  ALEDLMARAGASTRTRPLEQKLISE EDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: UBAP1 ubiquitin associated protein 1 [ Homo sapiens (human) ]
• Official Symbol: UBAP1
• Synonyms: UAP; UBAP; NAG20; SPG80; UBAP-1
• Gene ID: 51271
• mRNA Refseq: NM_016525.5
• Protein Refseq: NP_057609.2
• MIM: 609787
• UniProt ID: Q9NZ09