Recombinant Full Length Human UBASH3B Protein, C-Flag-tagged

• Cat.No.: UBASH3B-631HFL
• Product Overview: Recombinant Full Length Human UBASH3B Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a protein that contains a ubiquitin associated domain at the N-terminus, an SH3 domain, and a C-terminal domain with similarities to the catalytic motif of phosphoglycerate mutase. The encoded protein was found to inhibit endocytosis of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 72.5 kDa
• AA Sequence: MAQYGHPSPLGMAAREELYSKVTPR RNRQQRPGTIKHGSALDVLLSMGFP RARAQKALASTGGRSVQAAC DWLFSHVGDPFLDDPLPREYVLYLR PTGPLAQKLSDFWQQSKQICGKNKA HNIFPHITLCQFFMCEDSKV DALGEALQTTVSRWKCKFSAPLPLE LYTSSNFIGLFVKEDSAEVLKKFAA DFAAEAASKTEVHVEPHKKQ LHVTLAYHFQASHLPTLEKLAQNID VKLGCDWVATIFSRDIRFANHETLQ VIYPYTPQNDDELELVPGDF IFMSPMEQTSTSEGWIYGTSLTTGC SGLLPENYITKADECSTWIFHGSYS ILNTSSSNSLTFGDGVLERR PYEDQGLGETTPLTIICQPMQPLRV NSQPGPQKRCLFVCRHGERMDVVFG KYWLSQCFDAKGRYIRTNLN MPHSLPQRSGGFRDYEKDAPITVFG CMQARLVGEALLESNTIIDHVYCSP SLRCVQTAHNILKGLQQENH LKIRVEPGLFEWTKWVAGSTLPAWI PPSELAAANLSVDTTYRPHIPISKL VVSESYDTYISRSFQVTKEI ISECKSKGNNILIVAHASSLEACTC QLQGLSPQNSKDFVQMVRKIPYLGF CSCEELGETGIWQLTDPPIL
  PLTHGPTGGFNWRETLLQETRTRPL EQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS

Gene Information

• Gene Name: UBASH3B ubiquitin associated and SH3 domain containing B [ Homo sapiens (human) ]
• Official Symbol: UBASH3B
• Synonyms: p70; STS1; STS-1; TULA2; TULA-2
• Gene ID: 84959
• mRNA Refseq: NM_032873.5
• Protein Refseq: NP_116262.2
• MIM: 609201
• UniProt ID: Q8TF42