Recombinant Full Length Mouse Amyloid-Like Protein 2(Aplp2) Protein, His-Tagged

• Cat.No.: RFL-25650MF
• Product Overview: Recombinant Full Length Mouse Amyloid-like protein 2(Aplp2) Protein (Q06335) (32-707aa), fused to N-terminal His tag, was expressed in E. coli.

Specification

• Source: E.coli expression system
• Species: Mus musculus (Mouse)
• Tag: His
• Form: Lyophilized powder
• Protein length: Full Length of Mature Protein (32-707)
• AA Sequence: GYIEALAANAGTGFAVAEPQIAMFC GKLNMHVNIQTGKWEPDPTGTKSCL GTKEEVLQYCQEIYPELQITNVMEA NQPVNIDSWCRRDKRQCKSHIVIPF KCLVGEFVSDVLLVPDNCQFFHQER MEVCEKHQRWHTLVKEACLTEGLTL YSYGMLLPCGVDQFHGTEYVCCPQT KTVDSDSTMSKEEEEEEEDEEDEEE DYDLDKSEFPTEADLEDFTEAAADE EEEDEEEGEEVVEDRDYYYDPFKGD DYNEENPTEPSSEGTISDKEIVHDV KVPPTPLPTNDVDVYFETSADDNEH ARFQKAKEQLEIRHRNRMDRVKKEW EEAELQAKNLPKTERQTLIQHFQAM VKALEKEAASEKQQLVETHLARVEA MLNDRRRIALENYLAALQSDPPRPH RILQALRRYVRAENKDRLHTIRHYQ HVLAVDPEKAAQMKSQVMTHLHVIE ERRNQSLSLLYKVPYVAQEIQEEID ELLQEQRADMDQFTSSISENPVDVR VSSEESEEIPPFHPLHPFPSLSENE DTQPELYHPMKKGSGMAEQDGGLIG AEEKVINSKNKMDENMVIDETLDVK EMIFNAERVGGLEEEPESVGPLRED FSLSSNALIGLLVIAVAIATVIVIS LVMLRKRQYGTISHGIVEVDPMLTP EERHLNKMQNHGYENPTYKYLEQMQ I
• Purity: Greater than 90% as determined by SDS-PAGE.
• Applications: SDS-PAGE
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Tris/PBS-based buffer, 6% Trehalose, pH 8.0
• Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
• Gene Name: Aplp2
• Synonyms: Aplp2; APPL2; Amyloid beta precursor like protein 2; Amyloid beta; A4 precursor-like protein 2; Amyloid protein homolog; Amyloid-like protein 2; APLP-2; CDEI box-binding protein; CDEBP; Sperm membrane protein YWK-II
• UniProt ID: Q06335

Gene Information

• Gene Name: Aplp2
• Synonyms: Aplp2; APPL2; Amyloid beta precursor like protein 2; Amyloid beta; A4 precursor-like protein 2; Amyloid protein homolog; Amyloid-like protein 2; APLP-2; CDEI box-binding protein; CDEBP; Sperm membrane protein YWK-II
• UniProt ID: Q06335

Reviews

11/16/2022

High purity, reduce the interference of impurities in the experiment.

02/22/2022

Production quality is very good, can be seen in the production of strict control of quality.

02/29/2020

The background in Western blot is very clean, indicating that the antibody has a weak ability to bind to non-target proteins, reducing the interference of non-specific signals.

01/18/2020

Stability of APLP2 has been verified in many experiments, and it can maintain stable performance no matter how the conditions change.

Q&As

How is the clinical trial progress of APLP2 ? 💉

Clinical trials of APLP2 are still in the early stages, and more experimental validation and clinical trials are needed.

What is the synthesis method of APLP2 ? 🔬

The synthesis of APLP2 can be carried out in the cell expression system through genetic engineering technology.

What is the clinical application prospect of APLP2 ? 🔬

The recombinant APLP2 protein may be used clinically to treat clinical problems associated with neurodegenerative diseases.

What role does APLP2 play in the function of neurons? 🧠

APLP2 may play an important role in synaptic formation and plasticity regulation of neurons.

What are the structural and functional characteristics of APLP2 ? 🔬

APLP2 is a transmembrane protein that is mainly involved in the regulation of nerve cell growth and synaptic development.

What is the role of APLP2 in cell signaling? 🔍

APLP2 may be involved in cell signaling, but the specific mechanism needs further study.

Is APLP2 associated with synaptic plasticity? 🧠

Recombinant APLP2 may be involved in the regulation of synaptic plasticity, but the specific mechanism needs further study.

Is there a variant or mutation of APLP2 ? 🧬

Some variants and mutations of APLP2 s have been found, but their biological functions require more research.

What is the relationship between APLP2 and brain diseases? 🧠

The recombinant APLP2 protein may play a role in some neurodegenerative diseases, such as Alzheimer's disease.

How to obtain the related research literature of APLP2 ? 📚

You can search relevant academic databases or literature search platforms for research on APLP2 .

How to prepare high-purity samples of APLP2 ? 🧪

The preparation of high purity APLP2 requires strict purification steps such as affinity chromatography and ion exchange chromatography.

What is the use of recombinant APLP2 in the diagnosis of neurodegenerative diseases? 🏥

At present, the specific application of APLP2 in the diagnosis of neurodegenerative diseases has not been reported.

Can recombinant APLP2 be used as a drug target for neurodegenerative diseases? 💊

The recombinant APLP2 protein may play an important role in the pathogenesis of neurodegenerative diseases and can therefore be used as a potential drug target.

What is the difference between APLP2 and other related proteins? 🔍

There may be some structural and functional differences between APLP2 and other related proteins, which need further study.

What are the applications of APLP2 in scientific research? 🔬

APLP2 has been widely used in the fields of neuroscience, cell biology and molecular biology.

What is the relationship between APLP2 and AD (Alzheimer's disease)? 🧠

APLP2 may have a certain relationship with the occurrence and development of Alzheimer's disease, but the specific mechanism is not fully understood.

What is the effect of APLP2 on neuron growth? 🧠

APLP2 may promote neuron growth, but the detailed mechanism still needs to be further explored.

What is the relevance of recombinant APLP2 to the treatment of neurodegenerative diseases? 💊

APLP2 may play a role in the treatment of neurodegenerative diseases, but the specific treatment strategy is still to be studied.

What is the stability of APLP2 ? 🧪

The stability of APLP2 is affected by various factors, such as temperature, pH, etc., and it needs reasonable preservation conditions.

What are the side effects of APLP2? 🤔

There have been no reported side effects from the use of APLP2, but further studies are needed before use.