Recombinant Full Length Pan Troglodytes C-X-C Chemokine Receptor Type 4(Cxcr4) Protein, His-Tagged
Cat.No. : | RFL19138PF |
Product Overview : | Recombinant Full Length Pan troglodytes C-X-C chemokine receptor type 4(CXCR4) Protein (P61072) (1-352aa), fused to N-terminal His tag, was expressed in E. coli. |
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Source : | E.coli expression system |
Species : | Pan troglodytes (Chimpanzee) |
Tag : | His |
Form : | Lyophilized powder |
Protein length : | Full Length (1-352) |
AA Sequence : | MEGISIYTSDNYTEEMGSGDYDSMK EPCFREENANFNKIFLPTIYSIIFL TGIVGNGLVI LVMGYQKKLRSMTDKYRLHLSVADL LFVITLPFWAVDAVANWYFGNFLCK AVHVIYTVNL YSSVLILAFISLDRYLAIVHATNSQ RPRKLLAEKVVYVGVWIPALLLTIP DFIFANVSEA DDRYICDRFYPNDLWVVVFQFQHIM VGLILPGIVILSCYCIIISKLSHSK GHQKRKALKT TVILILAFFACWLPYYIGISIDSFI LLEIIKQGCEFENTVHKWISITEAL AFFHCCLNPI LYAFLGAKFKTSAQHALTSVSRGSS LKILSKGKRGGHSSVSTESESSSFH SS |
Purity : | Greater than 90% as determined by SDS-PAGE. |
Applications : | SDS-PAGE |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. |
Storage : | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Tris/PBS-based buffer, 6% Trehalose, pH 8.0 |
Reconstitution : | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference. |
Gene Name : | CXCR4 |
Synonyms : | CXCR4; C-X-C chemokine receptor type 4; CXC-R4; CXCR-4; Fusin; Stromal cell-derived factor 1 receptor; SDF-1 receptor; CD antigen CD184 |
UniProt ID : | P61072 |
Gene Name : | CXCR4 |
Synonyms : | CXCR4; C-X-C chemokine receptor type 4; CXC-R4; CXCR-4; Fusin; Stromal cell-derived factor 1 receptor; SDF-1 receptor; CD antigen CD184 |
UniProt ID : | P61072 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionCXCR4 participates in chemotaxis and migration of immune cells, facilitating their movement toward specific tissues during the immune response.
Specific chemokines or ligands, such as CXCL12, bind to CXCR4, influencing its role in immune cell activation and recruitment.
CXCR4 is predominantly localized on the cell surface of immune cells, particularly within the membrane of T cells and monocytes.
Dysregulation or abnormal expression of CXCR4 is associated with diseases such as cancer, HIV/AIDS, and autoimmune disorders, particularly affecting immune cell function.
There are potential therapeutic implications related to CXCR4 in diseases involving immune dysregulation and inflammation, making it a target for drug development.
CXCR4 contributes to the regulation of inflammatory responses and immune cell trafficking in various tissues, influencing the outcome of immune reactions.
C-X-C chemokine receptor type 4 (CXCR4) plays a crucial role in cellular processes, primarily contributing to immune responses and cell migration.
Customer Reviews (3)
Write a reviewThe responsive customer support team provided quick resolutions to any queries or issues we encountered.
The product's cost-effectiveness and clear instructions were instrumental in our experimental design.
We found the product's straightforward protocols highly conducive to seamless integration into our lab work.
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