Recombinant Full Length Rabbit Alpha-1D Adrenergic Receptor(Adra1D) Protein, His-Tagged
Cat.No. : | RFL-11700OF |
Product Overview : | Recombinant Full Length Rabbit Alpha-1D adrenergic receptor(ADRA1D) Protein (O02666) (1-576aa), fused to N-terminal His tag, was expressed in E. coli. |
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Source : | E.coli expression system |
Species : | Oryctolagus cuniculus (Rabbit) |
Tag : | His |
Form : | Lyophilized powder |
Protein length : | Full Length (1-576) |
AA Sequence : | MTFRDLLSVTFEGPRPDISAGGSGA GGGAGAGAGAGDTASSESPAVGGVP GAAGGGGGGS VVGAGSGEDNRSSAGEPGGAGGGGE VNGTAAVGGLVVSAQSVGVGVFLAA FILTAVAGNL LVILSVACNRHLQTVTNYFIVNLAV ADLLLSATVLPFSATMEVLGFWAFG RAFCDVWAAV DVLCCTASILSLCTISVDRYVGVRH SLKYPAIMTERKAAAILALLWAVAL VVSMGPLLGW KEPVPPDERFCGITEEVGYAVFSSL CSFYLPMAVIVVMYCRVYVVARSTT RSLEAGVKRE RGKASEVVLRIHCRGAASGADGAPG TRGAKGHTFRSSLSVRLLKFSREKK AAKTLAIVVG VFVLCWFPFFFVLPLGSLFPQLKPS EGVFKVIFWLGYFNSCVNPLIYPCS SREFKRAFLR LLRCQCRRRRRRRPLWRVYGHHWRA SAGGGPHPDCALSAGAALPGAALAL TAAPAPSSAA APEGQAAGAGRRKPPCAFREWRLLG PLRRPTTQLRAKVSSLSHKIRAGGA QRAEAACALR SEVEAVALSVARDVAEDNTCQAYEL ADYRNLRETDI |
Purity : | Greater than 90% as determined by SDS-PAGE. |
Applications : | SDS-PAGE |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. |
Storage : | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Tris/PBS-based buffer, 6% Trehalose, pH 8.0 |
Reconstitution : | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference. |
Gene Name : | ADRA1D |
Synonyms : | ADRA1D; Alpha-1D adrenergic receptor; Alpha-1D adrenoreceptor; Alpha-1D adrenoceptor |
UniProt ID : | O02666 |
Gene Name : | ADRA1D |
Synonyms : | ADRA1D; Alpha-1D adrenergic receptor; Alpha-1D adrenoreceptor; Alpha-1D adrenoceptor |
UniProt ID : | O02666 |
Products Types
◆ Recombinant Protein | ||
ADRA1D-196R | Recombinant Rat ADRA1D Protein, His (Fc)-Avi-tagged | +Inquiry |
Adra1d-3318M | Recombinant Mouse Adra1d, His-tagged | +Inquiry |
ADRA1D-540R | Recombinant Rat ADRA1D Protein | +Inquiry |
ADRA1D-3317H | Recombinant Human ADRA1D, His-tagged | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (17)
Ask a questionThe ADRA1D receptor plays a role in regulating the constriction of blood vessels, which affects blood pressure. Dysfunction of the ADRA1D receptor may contribute to the development of hypertension (high blood pressure).
Understanding the function of the ADRA1D protein and its role in different medical conditions can allow researchers to develop more targeted and effective treatments. Additionally, identifying potential genetic mutations in the ADRA1D gene can help with the diagnosis and treatment of certain disorders.
Yes, drugs that target the ADRA1D protein can interact with other medications, including other blood pressure medications, antidepressants, and medications used to treat erectile dysfunction.
Side effects of drugs that target the ADRA1D protein may include dizziness, headaches, fatigue, nausea, and abdominal pain. More serious side effects can include low blood pressure, palpitations, and difficulty breathing.
Yes, genetic mutations in the ADRA1D gene can affect the function of the ADRA1D protein, potentially leading to altered vasoconstriction, urinary tract function, and neurotransmitter release.
There are no known mutations in the ADRA1D gene that cause disease, but certain genetic variations in this gene may be associated with an increased risk of certain conditions, such as hypertension.
Drugs that target the ADRA1D protein are typically available in oral tablets or capsules. They can also be administered as injections in a medical setting.
Yes, there is ongoing research on the ADRA1D protein and its potential role in various medical conditions. Researchers are also exploring new drug targets and treatments that target the ADRA1D protein.
Dysfunction of the ADRA1D receptor may be associated with various medical conditions, including hypertension, lower urinary tract symptoms, benign prostatic hyperplasia, and depression.
The ADRA1D protein has been implicated in the development of several medical conditions, including hypertension, urinary incontinence, and neurological disorders such as schizophrenia and bipolar disorder.
Yes, certain natural substances have been found to target the ADRA1D receptor, including elderflower extract and apigenin, a flavonoid found in fruits and vegetables.
Yes, targeting the ADRA1D receptor can be a potential therapeutic strategy for certain medical conditions, such as hypertension, lower urinary tract symptoms, and depression. However, further research is needed to fully understand its role and potential therapeutic applications.
Yes, there are drugs that target the ADRA1D receptor, including selective alpha-1 adrenergic receptor antagonists (such as prazosin) and alpha-1 adrenergic agonists (such as phenylephrine).
There is some evidence that the ADRA1D receptor may be involved in the development of neurodegenerative diseases, such as Alzheimer's disease. However, further research is needed to fully understand its role in these conditions.
The use of drugs that target the ADRA1D protein during pregnancy or breastfeeding has not been extensively studied and should be used with caution. Pregnant or breastfeeding individuals should consult with their healthcare provider before using these medications.
Yes, several drugs that target the ADRA1D protein have been developed, including prazosin and doxazosin, which are commonly used to treat high blood pressure.
The ADRA1D receptor is expressed in the smooth muscle cells of the bladder and urethra, and its activation causes relaxation of these muscles. Dysfunction of the ADRA1D receptor may contribute to lower urinary tract symptoms, such as difficulty in urination and urinary incontinence.
Customer Reviews (5)
Write a reviewThanks to the excellent technical support provided by the manufacturer, any queries or concerns I had were promptly resolved, making the entire process seamless and hassle-free.
The ADRA1D protein provided by the manufacturer is of exceptional quality and meets all of my experimental requirements with high specificity and activity.
I also appreciate the detailed protocols and technical information provided by the manufacturer, which have been a valuable resource throughout my project.
the purity and stability of the protein are unparalleled, ensuring reproducible experimental results every time.
I am extremely satisfied with my experience with this product and the manufacturer's outstanding support team, and I highly recommend their products and services.
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