Recombinant Full Length Rat Cannabinoid Receptor 1(Cnr1) Protein, His-Tagged
Cat.No. : | RFL35759RF |
Product Overview : | Recombinant Full Length Rat Cannabinoid receptor 1(Cnr1) Protein (P20272) (1-473aa), fused to N-terminal His tag, was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
- Download
Source : | E.coli expression system |
Species : | Rattus norvegicus (Rat) |
Tag : | His |
Form : | Lyophilized powder |
Protein length : | Full Length (1-473) |
AA Sequence : | MKSILDGLADTTFRTITTDLLYVGS NDIQYEDIKGDMASKLGYFPQKFPL TSFRGSPFQE KMTAGDNSPLVPAGDTTNITEFYNK SLSSFKENEENIQCGENFMDMECFM ILNPSQQLAI AVLSLTLGTFTVLENLLVLCVILHS RSLRCRPSYHFIGSLAVADLLGSVI FVYSFVDFHV FHRKDSPNVFLFKLGGVTASFTASV GSLFLTAIDRYISIHRPLAYKRIVT RPKAVVAFCL MWTIAIVIAVLPLLGWNCKKLQSVC SDIFPLIDETYLMFWIGVTSVLLLF IVYAYMYILW KAHSHAVRMIQRGTQKSIIIHTSED GKVQVTRPDQARMDIRLAKTLVLIL VVLIICWGPL LAIMVYDVFGKMNKLIKTVFAFCSM LCLLNSTVNPIIYALRSKDLRHAFR SMFPSCEGTA QPLDNSMGDSDCLHKHANNTASMHR AAESCIKSTVKIAKVTMSVSTDTSA EAL |
Purity : | Greater than 90% as determined by SDS-PAGE. |
Applications : | SDS-PAGE |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. |
Storage : | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Tris/PBS-based buffer, 6% Trehalose, pH 8.0 |
Reconstitution : | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference. |
Gene Name : | Cnr1 |
Synonyms : | Cnr1; Skr6; Cannabinoid receptor 1; CB-R; CB1; Brain-type cannabinoid receptor |
UniProt ID : | P20272 |
Gene Name : | Cnr1 |
Synonyms : | Cnr1; Skr6; Cannabinoid receptor 1; CB-R; CB1; Brain-type cannabinoid receptor |
UniProt ID : | P20272 |
Products Types
◆ Recombinant Protein | ||
CNR1-1597H | Recombinant Human CNR1 Protein, GST-tagged | +Inquiry |
CNR1-1498R | Recombinant Rat Cnr1 Protein | +Inquiry |
CNR1-2711H | Recombinant Human CNR1 Protein, His-tagged | +Inquiry |
CNR1-772R | Recombinant Rhesus Macaque CNR1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Cnr1-8166R | Recombinant Rat Cnr1 protein, His & T7-tagged | +Inquiry |
◆ Lysates | ||
CNR1-7395HCL | Recombinant Human CNR1 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-1180 | CNR1 CHO-K1 β-Arrestin GPCR Assay Kit | +Inquiry |
Kit-1179 | cAMP CNR1 (CB1) CHO-K1 GPCR Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionThe protein receptor agonists can bind to receptors, activate receptors, and promote their signal transduction, resulting in physiological effects. CNR1 receptor antagonists, on the other hand, can bind to the receptor and prevent endocannabinoids from binding to the receptor, thereby inhibiting its signal transduction.
There are many types of mutations in the CNR1 gene, including single nucleotide substitution, insertion, or deletion. These mutations may cause structural and functional changes in the CNR1 receptor, affecting its binding and signal transduction to endocannabinoids.
CNR1 receptors play an important role in neuronal connections and neural circuits. It is involved in the growth, differentiation, and synapse formation of neurons, as well as in the regulation of neural circuits and signal transduction.
CNR1 receptors have potential applications in drug development. Some studies have shown that CNR1 receptor agonists or antagonists can be used to treat neurological disorders such as pain, depression, and anxiety.
Polymorphisms in the CNR1 gene may cause differences in individual responses to medications. Some polymorphisms may increase an individual's sensitivity or tolerance to medications, which can affect the efficacy and safety of medications.
For example, some drugs, toxins, or stressors may affect the expression level of the CNR1 gene, thus affecting its function and signal transduction processes.
Customer Reviews (3)
Write a reviewDNA binding ability is strong, and it performs well in related experiments.
The immunogenicity is very weak, does not cause an immune response, and has a high safety profile.
CNR1 has a long shelf life and good stability, which is convenient for the continuity of subsequent experiments.
Ask a Question for All Cnr1 Products
Required fields are marked with *
My Review for All Cnr1 Products
Required fields are marked with *
Inquiry Basket