Recombinant Full Length Rat D(2) Dopamine Receptor(Drd2) Protein, His-Tagged

• Cat.No.: RFL29848RF
• Product Overview: Recombinant Full Length Rat D(2) dopamine receptor(Drd2) Protein (P61169) (1-444aa), fused to N-terminal His tag, was expressed in E. coli.

Specification

• Source: E.coli expression system
• Species: Rattus norvegicus (Rat)
• Tag: His
• Form: Lyophilized powder
• Protein length: Full Length (1-444)
• AA Sequence: MDPLNLSWYDDDLERQNWSRPFNGS EGKADRPHYNYYAMLLTLLIFIIVF GNVLVCMAVS REKALQTTTNYLIVSLAVADLLVAT LVMPWVVYLEVVGEWKFSRIHCDIF VTLDVMMCTA SILNLCAISIDRYTAVAMPMLYNTR YSSKRRVTVMIAIVWVLSFTISCPL LFGLNNTDQN ECIIANPAFVVYSSIVSFYVPFIVT LLVYIKIYIVLRKRRKRVNTKRSSR AFRANLKTPL KGNCTHPEDMKLCTVIMKSNGSFPV NRRRMDAARRAQELEMEMLSSTSPP ERTRYSPIPP SHHQLTLPDPSHHGLHSNPDSPAKP EKNGHAKIVNPRIAKFFEIQTMPNG KTRTSLKTMS RRKLSQQKEKKATQMLAIVLGVFII CWLPFFITHILNIHCDCNIPPVLYS AFTWLGYVNS AVNPIIYTTFNIEFRKAFMKILHC
• Purity: Greater than 90% as determined by SDS-PAGE.
• Applications: SDS-PAGE
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Tris/PBS-based buffer, 6% Trehalose, pH 8.0
• Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
• Gene Name: Drd2
• Synonyms: Drd2; D(2 dopamine receptor; Dopamine D2 receptor
• UniProt ID: P61169

Gene Information

• Gene Name: Drd2
• Synonyms: Drd2; D(2 dopamine receptor; Dopamine D2 receptor
• UniProt ID: P61169

Reviews

01/10/2019

Integral to our research success, highly recommended.

03/26/2018

Efficiency at its best, a research cornerstone.

03/26/2018

Swift and accurate service, accelerates research timelines.

Q&As

What potential therapeutic applications arise from targeting DRD2 in neurological disorders?

Targeting DRD2 could treat disorders like Parkinson's and schizophrenia.

How do genetic variations in DRD2 affect behavior?

Genetic variations in DRD2 influence behavioral and mental health responses.

How does DRD2 contribute to motor control?

It regulates motor control via dopamine pathways.

How does DRD2 interact with other dopamine receptors?

DRD2 collaborates with other dopamine receptors in brain functions.

What is the primary role of DRD2 in neurotransmission?

DRD2 modulates neurotransmitter signaling in the brain.

What role does DRD2 play in psychiatric disorders?

DRD2 is key in psychiatric conditions, affecting mood and cognition.

What is the impact of altered DRD2 activity on addiction?

Altered DRD2 activity is linked to addiction, affecting reward mechanisms.