Recombinant HCoV-229E N protein, His-tagged

• Cat.No.: N-236V
• Product Overview: HCoV-229E Nucleocapsid, His Tag is expressed from E.coli cells. It contains AA Met 1-Asn 389 (Accession # P15130-1).

Specification

• Description: Nucleocapsid protein is a most abundant protein of coronavirus. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. While screening for ADP-ribosylated proteins during coronavirus (CoV) infection, we identified as the viral nucleocapsid (N) protein. Novel post-translation modification of the CoV N protein that may play a regulatory role for this important structural protein. The array of diverse functional activities accommodated in the hantaviral N protein goes far beyond to be a static structural protein and makes it an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
• Source: E. coli
• Species: HCoV-229E
• Tag: His
• Predicted N Terminal: His
• Form: Please contact us for detailed information.
• Molecular Mass: The protein has a calculated MW of 45.3 kDa.
• Protein length: Met 1-Asn 389
• Storage: For long term storage, the product should be stored at lyophilized state at -20°C or lower.
  Please avoid repeated freeze-thaw cycles.
  This product is stable after storage at:
  -20°C to -70°C for 12 months in lyophilized state;
  -70°C for 3 months under sterile conditions after reconstitution.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: N nucleocapsid protein [ Human coronavirus 229E ]
• Official Symbol: N
• Synonyms: Nucleocapsid protein; NP; Protein N; COVID-19
• Gene ID: 918763
• Protein Refseq: NP_073556.1
• UniProt ID: P15130