Recombinant HCV NS3 Protein
Cat.No. : | NS3-37H |
Product Overview : | This recombinant protein contains immunodominant regions of HCV NS3 protein with a MW of 40 kDa. It is recognized by positive samples in ELISA tests. |
- Specification
- Gene Information
- Related Products
Description : | HCV is a positive, single-stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins including NS3, and several non-structural proteins necessary for viral replication. The NS3 part of the polyprotein displays three enzymatic activities: serine protease, NTPase and RNA helicase. The NS3 serine proteinase (NS3P) is a non-structural hepatitis C protein responsible for proteolytic processing of other non-structural proteins; because of this, it is also the most extensively studied protein of the Hepatitis C genome. It is responsible for proteolytic processing of the entire downstream region of the HC polyprotein, catalyzing cleavage at the NS3/NS4a, NS4a/NS4b, NS4b/NS5a, and NS5a/NS5b sites to release the mature NS3, NS4a, NS4b, NS5a, and NS5b proteins.For proper function, NS3 requires NS4a as a cofactor, but, interestingly enough, NS3 also cleaves the NS4a protein. The molecular weight of the monomer NS3P is 70 kDa. |
Source : | E. coli |
Species : | HCV |
Form : | Affinity purified, liquid |
Molecular Mass : | 40 kDa |
Purity : | >95% pure by SDS-PAGE |
Applications : | Suitable for use in ELISA, Lateral Flow, WB, and other immune tests. |
Storage : | Upon receipt, store at 2-8 centigrade. |
Storage Buffer : | Tris-buffer, pH 8.0 |
Preservative : | 0.1% ProClin 300 |
Synonyms : | NS3; HCV NS3; Hepatitis C Virus NS3 |
Synonyms : | NS3; HCV NS3; Hepatitis C Virus NS3 |
Products Types
◆ Recombinant Protein | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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