Recombinant HPV18 major capsid L1 protein, His-tagged
| Cat.No. : | L1-01H |
| Product Overview : | Recombinant HPV18 major capsid L1 protein with C-terminal His6 fusion tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
| Description : | Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment. This binding mediates a conformational change in the virus capsid that facilitates efficient infection. The virion enters the host cell via endocytosis. During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2. |
| Source : | E. coli |
| Species : | Human Papillomavirus Type 18 |
| Tag : | His |
| Form : | Buffered aqueous solution |
| Molecular Mass : | 58.9 kDa |
| Protein length : | 527 |
| AA Sequence : | MRNVNVFPIFLQMALWRPSDNTVYL PPPSVARVVNTDDYVTPTSIFYHAG SSRLLTVGNPYFRVPAGGGNKQDIP KVSAYQYRVFRVQLPDPNKFGLPDT SIYNPETQRLVWACAGVEIGRGQPL GVGLSGHPFYNKLDDTESSHAATSN VSEDVRDNVSVDYKQTQLCILGCAP AIGEHWAKGTACKSRPLSQGDCPPL ELKNTVLEDGDMVDTGYGAMDFSTL QDTKCEVPLDICQSICKYPDYLQMS ADPYGDSMFFCLRREQLFARHFWNR AGTMGDTVPQSLYIKGTGMPASPGS CVYSPSPSGSIVTSDSQLFNKPYWL HKAQGHNNGVCWHNQLFVTVVDTTP STNLTICASTQSPVPGQYDATKFKQ YSRHVEEYDLQFIFQLCTITLTADV MSYIHSMNSSILEDWNFGVPPPPTT SLVDTYRFVQSVAITCQKDAAPAEN KDPYDKLKFWNVDLKEKFSLDLDQY PLGRKFLVQAGLRRKPTIGPRKRSA PSATTSSKPAKRVRVRARKHHHHHH HH |
| Endotoxin : | ＜1EU/ug by LAL |
| Purity : | ＞90% by SDS-PAGE |
| Applications : | Antigen for antibody production ELISA |
| Storage : | Store it under sterile conditions at -20 to -80 ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Concentration : | 0.98 mg/ml |
| Storage Buffer : | Solution in PBS, 0.05%SKL, pH7.4 |
| Gene Name : | L1 |
| Official Symbol : | major capsid L1 protein |
| Synonyms : | major capsid L1 protein |
| Gene ID : | 1489090 |
| mRNA Refseq : | X05015.1 |
| Protein Refseq : | NP_040317.1 |
| UniProt ID : | P06794 |
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| ◆ Recombinant Protein | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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