Recombinant Human ABCC1 Protein (1248-1531 aa), His-tagged
Cat.No. : | ABCC1-2325H |
Product Overview : | Recombinant Human ABCC1 Protein (1248-1531 aa) is produced by E. coli expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Signal Transduction. Protein Description: Partial. |
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Description : | Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Tris-based buffer,50% glycerol |
Molecular Mass : | 35.9 kDa |
Protein length : | 1248-1531 aa |
AA Sequence : | VRMSSEMETNIVAVERLKEYSETEK EAPWQIQETAPPSSWPQVGRVEFRN YCLRYREDLDFVLRHINVTINGGEK VGIVGRTGAGKSSLTLGLFRINESA EGEIIIDGINIAKIGLHDLRFKITI IPQDPVLFSGSLRMNLDPFSQYSDE EVWTSLELAHLKDFVSALPDKLDHE CAEGGENLSVGQRQLVCLARALLRK TKILVLDEATAAVDLETDDLIQSTI RTQFEDCTVLTIAHRLNTIMDYTRV IVLDKGEIQEYGAPSDLLQQRGLFY SMA kDaGLV |
Purity : | > 90% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA will be sent along with the products. Please refer to it for detailed information. |
Gene Name : | ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 [ Homo sapiens ] |
Official Symbol : | ABCC1 |
Synonyms : | ABCC1; GS X; LTC4 transporter; 26; MRP; ABCC; GS-X; MRP1; ABC29; DKFZp781G125; DKFZp686N04233; |
Gene ID : | 4363 |
mRNA Refseq : | NM_004996 |
Protein Refseq : | NP_004987 |
MIM : | 158343 |
UniProt ID : | P33527 |
Products Types
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ABCC1-57R | Recombinant Rat ABCC1 Protein, His (Fc)-Avi-tagged | +Inquiry |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (16)
Ask a questionYes, you can communicate with our experts about specific customization needs.
In-stock products will be shipped as soon as possible after your purchase, and the specific arrival time will vary from address to address.
Our product manuals generally include relevant information, or you can contact our technical experts at any time and they will be able to give you relevant assistance.
You can communicate directly with our experts.
Yes, ABCC1 protein, including custom-produced ABCC1 protein, is participating in this promotion.
Our experts can advise on your research needs.
Protein purification is generally performed by hydrophobic chromatography, affinity chromatography, ion exchange chromatography, salting out, molecular sieve, etc.
We offer a wide range of protein expression systems, including common bacterial expression systems, baculovirus-insect cell expression systems, cell-free in vitro protein expression systems, mammalian expression systems, yeast expression systems, etc.
ABCC1 protein is ubiquitously expressed in most normal tissues.
You can communicate directly with us about your specific purchase needs, and we will determine if there is a discount based on the actual situation.
We also offer ABCC2, ABCC3, ABCC4, ABCC6 proteins, or you can get the protein you need through our custom protein production service.
Membrane can be blocked in 5% milk before incubation with primary antibody.
Generally, nitrocellulose membrane and PVDF membrane are used for Western Blot.
Several studies have shown that multidrug resistance is associated with enhanced ABCC1 protein expression.
Yes, ABCC1 causes resistance to natural product drugs such as epipodophyllotoxins, vinca alkaloids and certain anthracyclines.
ABCC1-6, ABCC10-13 all belong to the MRP family.
Customer Reviews (5)
Write a reviewThe protein meets the custom requirements, great price and the technician can give me professional help.
The technicians provided me with a lot of after-sales help, and the bands obtained for WB are also very clear.
Just participated in this promotion. High protein purity and good experimental results.
Right price, fast delivery and good after-sales service.
Fast delivery and high quality product.
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