Recombinant Human ACAN Protein, His-tagged

• Cat.No.: ACAN-29H
• Product Overview: Recombinant Human ACAN Protein (Ala2162-Pro2316) with N-His tag was expressed in E. coli.

Specification

• Description: This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene.
• Source: E. coli
• Species: Human
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 23.7 kDa
• Protein length: Ala2162-Pro2316
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1 mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: ACAN aggrecan [ Homo sapiens (human) ]
• Official Symbol: ACAN
• Synonyms: ACAN; aggrecan; AGC1; SEDK; AGCAN; CSPG1; MSK16; CSPGCP; SSOAOD; aggrecan core protein; cartilage-specific proteoglycan core protein; chondroitin sulfate proteoglycan core protein 1; large aggregating proteoglycan
• Gene ID: 176
• mRNA Refseq: NM_013227
• Protein Refseq: NP_037359
• MIM: 155760
• UniProt ID: P16112