Recombinant Human ACE Protein, C-His-tagged
Cat.No. : | ACE-025H |
Product Overview : | Recombinant Human ACE Protein with C-His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Angiotensin-converting enzyme (ACE) is a carboxy-terminal dipeptidyl exopeptidase that converts Angiotensin I to the potent vasopressive hormone, Angiotensin II. There are two isoforms of ACE, the pulmonary ACEP and the testicular ACET. ACEP is a glycoprotein expressed in vascular endothelial cells of the lung, liver, adrenal cortex, pancreas, kidney and spleen. The ACET isoform is expressed exclusively in adult testis by developing sperm cells, specifically, late pachytene spermatocytes. Additionally, ACE inactivates bradykinin, a vasodepressor peptide, and is involved in fluid/electrolyte homeostasis. Although it bears significant sequence homology to ACE, ACE2 shows a more restricted pattern of expression. ACE is expressed ubiquitously throughout the vasculature while ACE2 is expressed only in cardiac, renal and testicular cells. |
Source : | E. coli |
Species : | Human |
Tag : | C-His |
Molecular Mass : | ~66 kDa |
AA Sequence : | LDPGLQPGNFSADEAGAQLFAQSYN SSAEQVLFQSVAASWAHDTNITAEN ARRQEEAALLSQEFAEAWGQKAKEL YEPIWQNFTDPQLRRIIGAVRTLGS ANLPLAKRQQYNALLSNMSRIYSTA KVCLPNKTATCWSLDPDLTNILASS RSYAMLLFAWEGWHNAAGIPLKPLY EDFTALSNEAYKQDGFTDTGAYWRS WYNSPTFEDDLEHLYQQLEPLYLNL HAFVRRALHRRYGDRYINLRGPIPA HLLGDMWAQSWENIYDMVVPFPDKP NLDVTSTMLQQGWNATHMFRVAEEF FTSLELSPMPPEFWEGSMLEKPADG REVVCHASAWDFYNRKDFRIKQCTR VTMDQLSTVHHEMGHIQYYLQYKDL PVSLRRGANPGFHEAIGDVLALSVS TPEHLHKIGLLDRVTNDTESDINYL LKMALEKIAFLPFGYLVDQWRWGVF SGRTPPSRYNFDWWYLRTKYQGICP PVTRNETHFDAGAKFHVPNVTPYIR YFVSFVLQFQFHEALCKEAGYEGPL HQCDIYRSTKAGAKLRKVLQAGSSR PWQEVLKDMVGLDALDAQPLLKYFQ PVTQWLQEQNQQNGEVLGWPEYQWH P |
Purity : | Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE). |
Notes : | For research use only, not for use in diagnostic procedure. |
Storage : | Store at 4 centigrade short term. Aliquot and store at -20 centigrade long term. Avoid freeze-thaw cycles. |
Concentration : | ≥0.5 mg/mL |
Storage Buffer : | PBS, 4M Urea, pH7.4 |
Gene Name : | ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 [ Homo sapiens (human) ] |
Official Symbol : | ACE |
Synonyms : | ACE; angiotensin I converting enzyme (peptidyl-dipeptidase A) 1; DCP1; angiotensin-converting enzyme; ACE1; CD143; kininase II; peptidase P; CD143 antigen; testicular ECA; carboxycathepsin; dipeptidyl carboxypeptidase 1; dipeptidyl carboxypeptidase I; angiotensin converting enzyme, somatic isoform; DCP; ICH; MVCD3; |
Gene ID : | 1636 |
mRNA Refseq : | NM_000789 |
Protein Refseq : | NP_000780 |
MIM : | 106180 |
UniProt ID : | P12821 |
Products Types
◆ Native Protein | ||
ACE-3047R | Native rabbit ACE | +Inquiry |
◆ Lysates | ||
ACE-9094HCL | Recombinant Human ACE 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-2409 | Angiotensin II Converting Enzyme (ACE2) Inhibitor Screening Kit | +Inquiry |
Kit-2408 | Angiotensin I Converting Enzyme (ACE1) Inhibitor Screening Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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