Recombinant Human ADAMDEC1, GST-tagged

• Cat.No.: ADAMDEC1-9384H
• Product Overview: Recombinant Human ADAMDEC1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This encoded protein is thought to be a secreted protein belonging to the disintegrin metalloproteinase family. Its expression is upregulated during dendritic cells maturation. This protein may play an important role in dendritic cell function and their interactions with germinal center T cells.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 56-470a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: ADAMDEC1 ADAM-like, decysin 1 [ Homo sapiens ]
• Official Symbol: ADAMDEC1
• Synonyms: ADAMDEC1; ADAM-like, decysin 1; ADAM DEC1; M12.219; decysin; disintegrin protease; ADAM-like protein decysin-1; a disintegrin and metalloproteinase domain-like protein decysin-1; FLJ79219
• Gene ID: 27299
• mRNA Refseq: NM_001145271
• Protein Refseq: NP_001138743
• MIM: 606393
• UniProt ID: O15204
• Chromosome Location: 8p12
• Function: metal ion binding; metalloendopeptidase activity; peptidase activity; zinc ion binding

Reviews

09/17/2022

This is a purchase experience that satisfies me, both in terms of product quality and after-sales service.

04/10/2021

The purchased ADAMEC1 protein is suitable for WB experiments, and the experiments went very well and satisfactory results were obtained

05/14/2020

The technical expert will follow up on the progress of my experiments and provide constructive advice on the problems that arise in my experiments

01/26/2020

The staff in charge of my after-sales service were very patient and provided me with a lot of help.

Q&As

Do your products arrive quickly?

We will arrange delivery as soon as possible after the customer purchases, but the specific arrival speed is also related to your address.

Do you offer endotoxin-free ADAMDEC1 protein?

We can perform endotoxin removal according to your needs.

Does ADAMDEC1 interact with THBS1?

Yes, THBS1 is a substrate for ADAMDEC1 action.

How do you perform protein purification?

We generally purify proteins by methods such as hydrophobic chromatography, affinity chromatography, ion exchange chromatography, salting out, molecular sieve, etc.

What biological processes is ADAMDEC1 involved in?

ADAMDEC1 is involved in multiple processes including immune response, cell adhesion, cell fusion, and protein hydrolysis.

Do you offer freeze-dried powder?

We offer both liquid and lyophilized powder.

Which protein does ADAMDEC1 have a higher homology with?

ADAMDEC1 is highly homologous to ADAM28.

In which diseases has ADAMDEC1 been studied?

ADAMDEC1 has been used in studies of lung cancer, glioblastoma, gastric cancer, and colorectal cancer, among other diseases.

What are the effects of overexpression of ADAMDEC1

Overexpression of ADAMDEC1 leads to proliferation of glioma cells and nuclear aggregation of BeWo cells and 3DJEG-3 cells.

In which tissues is ADAMDEC1 highly expressed?

ADAMDEC1 is predominantly expressed in human lymphocytes and spleen.

I want to buy ADAMDEC1 protein fused with other tags, do you offer it?

We can custom produce ADAMDEC1 protein according to your requirements.