Recombinant Human ADGRG5 protein, T7/His-tagged
Cat.No. : | ADGRG5-177H |
Product Overview : | Recombinant human GPR114 extracellular domain cDNA (22 - 250 aa, derived from BC032401) protein fused with T7-His-TEV cleavage site Tag at N-terminal was expressed in E. coli. |
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Source : | E. coli |
Species : | Human |
Tag : | T7/His |
Form : | 0.5 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, arginine, DTT and Glycerol. |
AA Sequence : | MASMTGGQQMGRGHHHHHHGNLYFQ GGEETWEELLSYMENMQVSRGRSSV FSSRQLHQLEQMLLNTSFPGYNLTL QTPTIQSLAFKLSCDFSGLSLTSAT LKRVPQAGGQHARGQHAMQFPAELT RDACKTRPRELRLICIYFSNTHFFK DENNSSLLNNYVLGAQLSHGHVNNL RDPVNISFWHNQSLEGYTLTCVFWK EGARKQPWGGWSPEGCRTEQPSHSQ VLCRCNHLTYFAVLMQLSPALVPAE LLAPLTY |
Purity : | >90% by SDS-PAGE. |
Storage : | Keep at -80°C for long term storage. Product is stable at 4 °C for at least 30 days. |
Gene Name : | ADGRG5 adhesion G protein-coupled receptor G5 [ Homo sapiens ] |
Official Symbol : | ADGRG5 |
Synonyms : | PGR27; GPR114; G protein-coupled receptor 114; G protein-coupled receptor PGR27 |
Gene ID : | 221188 |
mRNA Refseq : | NM_001304376 |
Protein Refseq : | NP_001291305 |
MIM : | |
UniProt ID : | Q8IZF4 |
Chromosome Location : | 16q21 |
Function : | G-protein coupled receptor activity |
Products Types
◆ Recombinant Protein | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionADGRG5 interacts with specific ligands or extracellular matrix components, leading to the activation of downstream signaling pathways, such as [specific signaling cascades or pathways].
ADGRG5 has known intracellular binding partners or interactors that modulate its signaling or functional properties, influencing [specific downstream events or cellular responses].
Pharmacological agents or genetic manipulations can modulate the function or expression of ADGRG5, offering potential therapeutic interventions for [specific disease conditions or clinical applications].
ADGRG5 signaling exhibits cross-talk with other signaling pathways, influencing cellular responses and physiological functions, suggesting interplay between [specific signaling pathways] and its implications in [relevant biological contexts].
Identified genetic variations or mutations in ADGRG5 have been associated with human diseases or phenotypic traits, such as [specific disease conditions or clinical characteristics], shedding light on its significance in [relevant disease mechanisms or phenotypic variations].
ADGRG5 is implicated in specific disease processes or pathological conditions, involving [specific disease mechanisms or molecular pathways], providing insights into its role in [relevant disease contexts].
The activity of ADGRG5 can be regulated by post-translational modifications, such as phosphorylation, ubiquitination, or glycosylation, which affect its signaling and functional properties.
ADGRG5 exhibits a distinct subcellular localization pattern, impacting its trafficking, signaling, and interaction with downstream effectors, primarily localized to [specific cellular compartments, such as plasma membrane or endosomes].
Activation of ADGRG5 results in functional consequences, including [relevant cellular processes, such as cell proliferation, differentiation, or migration], contributing to [specific physiological outcomes or functional outcomes].
ADGRG5 exhibits a specific expression pattern across different tissues and cell types, regulated under physiological and pathological conditions by [specific regulatory mechanisms or signaling pathways].
Customer Reviews (2)
Write a reviewDemonstrates superior thermal stability in protein denaturation studies.
Provides reliable and reproducible results in protein-protein interaction assays.
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