Recombinant Human ADRB2 cell lysate

• Cat.No.: ADRB2-34HCL

Specification

• Description: This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: ADRB2 adrenoceptor beta 2, surface [ Homo sapiens ]
• Official Symbol: ADRB2
• Synonyms: BAR; B2AR; ADRBR; ADRB2R; BETA2AR; beta-2 adrenergic receptor; beta-2 adrenoceptor; beta-2 adrenoreceptor; catecholamine receptoradrenoceptor beta 2 surface; adrenergic, beta-2-, receptor, surface
• Gene ID: 154
• mRNA Refseq: NM_000024
• Protein Refseq: NP_000015
• MIM: 109690
• UniProt ID: P07550
• Chromosome Location: 5q31-q32
• Pathway: Adrenergic signaling in cardiomyocytes, organism-specific biosystem; Arf6 signaling events, organism-specific biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem
• Function: adenylate cyclase binding; beta2-adrenergic receptor activity; norepinephrine binding