Recombinant Human AFG3L1P, GST-tagged

• Cat.No.: AFG3L1P-9458H
• Product Overview: Recombinant Human AFG3L1P protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-100a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: AFG3L1P AFG3 ATPase family member 3-like 1 (S. cerevisiae), pseudogene [ Homo sapiens (human) ]
• Official Symbol: AFG3L1P
• Synonyms: AFG3L1P; AFG3 ATPase family gene 3-like 1 (S. cerevisiae), pseudogene; AFG3 ATPase family gene 3-like 1 (S. cerevisiae); AFG3; AFG3 ATPase family gene 3-like 1 (S. cerevisiae) pseudogene; AFG3L1; AFG3 ATPase family gene 3-like 1 (yeast); AFG3 (ATPase family gene 3, yeast)-like 1
• Gene ID: 172
• mRNA Refseq: NR_003226.1
• MIM: 603020
• Chromosome Location: 16q24.3

Reviews

11/05/2022

Dissecting protein-protein interactions in cellular signaling for signal transduction.

04/12/2021

Probing protein-protein interactions in cell adhesion for tissue development.

04/03/2019

Mapping protein-protein interactions in immune cell activation for immune response.

Q&As

What is the role of AFG3L1P protein in mitochondrial function, cellular metabolism, or cellular stress response, and how can its function be investigated experimentally?

AFG3L1P protein plays a role in mitochondrial function, cellular metabolism, or cellular stress response, and its function can be investigated using techniques like metabolic profiling or gene knockdown approaches.

Are there any known post-translational modifications or regulatory mechanisms that modulate the activity or stability of AFG3L1P protein?

Post-translational modifications and regulatory mechanisms may modulate the activity or stability of AFG3L1P protein.

How does AFG3L1P protein contribute to cellular processes such as mitochondrial dynamics, proteostasis, or apoptosis, and what are the underlying molecular mechanisms?

AFG3L1P protein contributes to cellular processes such as mitochondrial dynamics, proteostasis, or apoptosis, and the underlying molecular mechanisms are currently being investigated.

Can AFG3L1P protein be targeted or manipulated to modulate mitochondrial function or treat mitochondrial disorders, and what are the potential implications for therapeutic interventions?

AFG3L1P protein holds potential as a target for modulating mitochondrial function or treating mitochondrial disorders, and further research is needed to explore its implications for therapeutic interventions.

What is the subcellular localization of AFG3L1P protein, and how can it be experimentally determined?

The subcellular localization of AFG3L1P protein can be experimentally determined using techniques such as immunofluorescence microscopy or subcellular fractionation.

Are there any genetic variations or mutations in the gene encoding AFG3L1P protein that impact its expression or function, and what are the implications for mitochondrial function or disease susceptibility?

Genetic variations or mutations in the gene encoding AFG3L1P protein may impact its expression or function, influencing mitochondrial function or disease susceptibility.

What experimental techniques or assays have been used to study the functional significance of AFG3L1P protein, such as co-immunoprecipitation, metabolic profiling, or gene knockdown approaches?

Various experimental techniques or assays, such as co-immunoprecipitation, metabolic profiling, or gene knockdown approaches, have been used to study the functional significance of AFG3L1P protein.

Does AFG3L1P protein interact with specific molecules or participate in protein complexes, and what are the functional implications of these interactions?

AFG3L1P protein may interact with specific molecules or participate in protein complexes, which have functional implications in cellular processes.

How does dysregulation or dysfunction of AFG3L1P protein affect mitochondrial homeostasis, cellular energetics, or disease development?

Dysregulation or dysfunction of AFG3L1P protein can disrupt mitochondrial homeostasis, impair cellular energetics, and contribute to disease development.

How is the expression of AFG3L1P protein regulated, and what factors or signaling pathways control its expression?

The expression of AFG3L1P protein is regulated by specific factors and signaling pathways.