Recombinant Human AGAP3 Protein, MYC/DDK-tagged
Cat.No. : | AGAP3-541H |
Product Overview : | Recombinant Human AGAP3, transcript variant 1, fused with MYC/DDK tag at C-terminal was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
- Download
Description : | This gene encodes an essential component of the N-methyl-D-aspartate (NMDA) receptor signaling complex which mediates long-term potentiation in synapses by linking activation of NMDA receptor to alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor trafficking. The encoded protein contains an N-terminal GTPase-like domain, a pleckstrin homology domain, an ArfGAP domain and several C-terminal ankryn repeat domains. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 97.8 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 [ Homo sapiens ] |
Official Symbol : | AGAP3 |
Synonyms : | AGAP3; ArfGAP with GTPase domain, ankyrin repeat and PH domain 3; centaurin, gamma 3 , CENTG3; arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3; centaurin-gamma-3; centaurin, gamma 3; CRAM-associated GTPase; MR1-interacting protein; CRMP (collapsin response mediator protein) associated; CRAG; AGAP-3; CENTG3; MRIP-1; cnt-g3; FLJ16146; FLJ34452; |
Gene ID : | 116988 |
mRNA Refseq : | NM_031946 |
Protein Refseq : | NP_114152 |
UniProt ID : | Q96P47 |
Products Types
◆ Recombinant Protein | ||
AGAP3-0009H | Recombinant Human AGAP3 Protein, GST-Tagged | +Inquiry |
Agap3-1551M | Recombinant Mouse Agap3 Protein, Myc/DDK-tagged | +Inquiry |
AGAP3-301203H | Recombinant Human AGAP3 protein, GST-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (23)
Ask a questionYes, AGAP3 belongs to a family of Arf GTPase-activating proteins (ArfGAPs) that share similar structural domains.
Yes, AGAP3 expression can vary between different tissues and cell types.
AGAP3 is primarily located in the cytoplasm of cells.
The molecular weight of AGAP3 is approximately 150 kDa.
Yes, AGAP3's involvement in vesicle trafficking is crucial for neuronal development and synaptic function.
AGAP3 is a protein that plays a role in intracellular trafficking and membrane dynamics.
AGAP3's involvement in vesicle trafficking and cell migration can contribute to tumor growth and metastasis in certain cancers.
AGAP3 acts as a GTPase-activating protein (GAP) for Arf GTPases, regulating their activity in intracellular trafficking pathways.
AGAP3 participates in endocytic processes by regulating the formation and trafficking of endocytic vesicles.
AGAP3's expression can be regulated by various factors, including cellular signaling pathways and transcriptional regulators.
The PH domain in AGAP3 is thought to be involved in membrane targeting and interaction with phospholipids.
AGAP3 influences cell migration by regulating the turnover of adhesion complexes and actin dynamics.
AGAP3 is involved in vesicle trafficking, endocytosis, and cell migration.
AGAP3 stands for Arf-GAP with GTPase domain, Ankyrin repeat, and PH domain 3.
Yes, AGAP3's function can be influenced by factors such as post-translational modifications and protein interactions.
The Ankyrin repeat in AGAP3 is believed to play a role in protein-protein interactions.
Researchers use techniques like molecular biology, microscopy, and cell culture experiments to study AGAP3's role in cells.
AGAP3 helps regulate the movement of vesicles within cells, aiding in the transportation of molecules.
Mutations in AGAP3 have been linked to certain neurological disorders and cancer progression.
Yes, AGAP3 can be found in various subcellular compartments, including the plasma membrane, endosomes, and Golgi apparatus.
Yes, AGAP3 can impact signal transduction pathways by regulating membrane trafficking of receptors and signaling molecules.
AGAP3's GAP activity is often activated by interactions with activated Arf GTPases, triggering the hydrolysis of GTP to GDP.
Knocking down or inhibiting AGAP3 can lead to disrupted vesicle trafficking, altered cell adhesion, and changes in cellular morphology.
Customer Reviews (5)
Write a reviewThe product’s high purity facilitated precise quantification, minimizing variability in our data.
Agap3's absence of contaminants contributed to data accuracy.
The product’s innovative characteristics allowed us to delve into previously unexplored cellular mechanisms.
The consistent effects of Agap3 streamlined our research process.
It triggered a robust immune response, evident in cytokine levels.
Ask a Question for All AGAP3 Products
Required fields are marked with *
My Review for All AGAP3 Products
Required fields are marked with *
Inquiry Basket