Recombinant Human AGER Protein (Aal23-Ser120), C-His tagged, Animal-free, Carrier-free

• Cat.No.: AGER-70H
• Product Overview: Recombinant Human AGER Protein (Aal23-Ser120) with C-His tag was expressed in E. coli and Animal-free as well as Carrier-free.

Specification

• Description: Receptor for advanced glycation endproducts (RAGE) is a 35 kDa transmembrane receptor of the immunoglobulin super family. The mature RAGE has three main parts, consisting of extracellular, transmembrane, and cytosolic regions. A central mechanism by which ligand-RAGE interaction mediates cell stress and upregulates inflammatory pathways is via activation of signal transduction pathways.
• Source: E. coli
• Species: Human
• Tag: C-His
• Form: Lyophilized
• Molecular Mass: The protein has a calculated MW of 30.94 kDa.
  The protein migrates as 40 kDa under reducing condition (SDS-PAGE analysis).
• Protein Length: Aal23-Ser120
• Endotoxin: < 0.1 EU/μg of the protein by the LAL method.
• Purity: >98% as determined by SDS-PAGE analysis.
• Storage: This product is stable after storage at:
  -20 centigrade for 12 months in lyophilized state from date of receipt.
  -20 or -80 centigrade for 1 month under sterile conditions after reconstitution.
  Avoid repeated freeze/thaw cycles.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 8.0.
• Reconstitution: It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
• Shipping: The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage.

Gene Information

• Gene Name: AGER advanced glycosylation end product-specific receptor [ Homo sapiens (human) ]
• Official Symbol: AGER
• Synonyms: AGER; advanced glycosylation end product-specific receptor; RAGE; RAGE isoform sRAGE-delta; RAGE isoform NtRAGE-delta
• Gene ID: 177
• mRNA Refseq: NM_001136
• Protein Refseq: NP_001127
• MIM: 600214
• UniProt ID: Q15109