Recombinant Human AIM2 Protein (S144-T343), His tagged
Cat.No. : | AIM2-0587H |
Product Overview : | Recombinant Human 6His-MBP-TEV-GG-AIM2(S144-T343 end) Protein was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precursor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Also acts as a mediator of pyroptosis, necroptosis and apoptosis (PANoptosis), an integral part of host defense against pathogens, in response to bacterial infection. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8. Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid |
Protein Length : | S144-T343 |
Endotoxin : | < 0.01 EU per μg of the protein |
Purity : | 90% |
Stability : | Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles |
Storage Buffer : | Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol |
Shipping : | It is shipped out with blue ice. |
Gene Name : | AIM2 absent in melanoma 2 [ Homo sapiens (human) ] |
Official Symbol : | AIM2 |
Synonyms : | AIM2; absent in melanoma 2; interferon-inducible protein AIM2; PYHIN4; |
Gene ID : | 9447 |
mRNA Refseq : | NM_004833 |
Protein Refseq : | NP_004824 |
MIM : | 604578 |
UniProt ID : | O14862 |
Products Types
◆ Recombinant Protein | ||
AIM2-415M | Recombinant Mouse AIM2 Protein, His (Fc)-Avi-tagged | +Inquiry |
AIM2-1159H | Recombinant Human AIM2 protein(Met1-Thr343), GST-tagged | +Inquiry |
AIM2-4939H | Recombinant Human AIM2 Protein, His-tagged | +Inquiry |
AIM2-0586H | Recombinant Human AIM2 Protein (S144-T343), Tag Free | +Inquiry |
AIM2-0211H | Recombinant Human AIM2 Protein (Met1-Lys342), N-His-tagged | +Inquiry |
◆ Lysates | ||
AIM2-636HCL | Recombinant Human AIM2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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