Recombinant Human AKR1C2 Protein, DYKDDDDK-tagged

• Cat.No.: AKR1C2-01H
• Product Overview: Recombinant protein from the full-length sequence of Homo sapiens aldo-keto reductase family 1 member C2 (AKR1C2), transcript variant 3 (NM_001135241), with a DYKDDDDK tag was expressed in human cells.

Specification

• Description: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.
• Source: Human Cell
• Species: Human
• Tag: DYKDDDDK
• Molecular Mass: 15.6 kDa
• Endotoxin: Endotoxin level is < 0.1 ng/μg of protein (<1 EU/μg)
• Purity: >90% by SDS-PAGE gel and Coomassie Blue staining
• Applications: Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
• Storage Buffer: Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives

Gene Information

• Gene Name: AKR1C2 aldo-keto reductase family 1 member C2 [ Homo sapiens (human) ]
• Official Symbol: AKR1C2
• Synonyms: AKR1C2; aldo-keto reductase family 1 member C2; DD; DD2; TDD; BABP; DD-2; DDH2; HBAB; HAKRD; MCDR2; SRXY8; DD/BABP; AKR1C-pseudo; aldo-keto reductase family 1 member C2; 3-alpha-HSD3; chlordecone reductase homolog HAKRD; dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III; pseudo-chlordecone reductase; testicular 17,20-desmolase deficiency; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; type II dihydrodiol dehydrogenase; EC 1.1.1.112; EC 1.1.1.209; EC 1.1.1.357; EC 1.1.1.53; EC 1.1.1.62; EC 1.3.1.20
• Gene ID: 1646
• mRNA Refseq: NM_001135241
• Protein Refseq: NP_001128713
• MIM: 600450
• UniProt ID: P52895