Recombinant Human ALKBH6, GST-tagged

• Cat.No.: ALKBH6-9587H
• Product Overview: Recombinant Human ALKBH6 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: C-term-169a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: ALKBH6 alkB, alkylation repair homolog 6 (E. coli) [ Homo sapiens ]
• Official Symbol: ALKBH6
• Synonyms: alkB, alkylation repair homolog 6 (E. coli); alkylation repair homolog 6; probable alpha-ketoglutarate-dependent dioxygenase ABH6; Alkylated DNA repair protein alkB homolog 6; EC 1.14.11.; MGC15677; ALKBH6
• Gene ID: 84964
• mRNA Refseq: NM_032878.3
• Protein Refseq: NP_116267.3
• MIM: 613304
• UniProt ID: Q3KRA9
• Chromosome Location: 19q13.12
• Function: metal ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; oxidoreductase activity, acting on single

Reviews

08/07/2021

Methods such as ELISA or immunostaining performed very well.

01/04/2021

It has good solubility and stability in solution.

09/27/2020

Prone to producing antibodies in animals or humans.

11/21/2019

Easily attached to the surface of cells or materials.

Q&As

How does mutation of Alkbh6 affect RNA modification?

Alkbh6, as an RNA modification enzyme, plays an important role in the modification of amino adenine (m1A). Mutations may result in reduced enzyme activity, which in turn affects RNA modification.

What is the mutation rate of Alkbh6 gene in the population?

No definitive statistical results have been obtained, but as of August 2021, four human single nucleotide polymorphism loci have been associated with mutations in the Alkbh6 gene.

Does Alkbh6 gene participate in DNA repair?

The Alkbh6 gene has not been shown to be involved in DNA repair.

Does Alkbh6 gene have a relationship with autism?

There is no clear link between the Alkbh6 gene and autism.

What is the Alkbh6 gene affect the occurrence of neurological diseases?

At present, there is not enough research evidence to show that Alkbh6 affects the development of neurological diseases.

How Alkbh6 gene affect human growth and development?

No studies have confirmed that Alkbh6 gene has an effect on human growth and development.

Can Alkbh6 gene be a tumor marker?

At present, it is still in the research stage, and it is not certain that Alkbh6 can be used as a tumor marker.

What is the Alkbh6 gene affect cardiovascular disease?

At present, there is not enough research evidence to show that Alkbh6 has an effect on cardiovascular disease.

Does Alkbh6 affect people's cognitive ability?

No studies have shown that Alkbh6 has an effect on cognitive ability.

Is there a relationship between Alkbh6 gene and cancer?

Some studies have shown that the expression level of Alkbh6 gene is increased in liver cancer, lung cancer and other malignant tumors, which may be related to the cancer process.

What diseases can Alkbh6 gene mutation cause?

Some studies have suggested that Alkbh6 gene mutation may be associated with a variety of malignant tumors, but the specific disease mechanism needs further research to confirm.

Does Alkbh6 have an effect on the human immune system?

The Alkbh6 gene has not been found to have an effect on the human immune system.

Does Alkbh6 gene participate in hormone metabolism?

No studies have shown that Alkbh6 is involved in hormone metabolism.

Is there a relationship between Alkbh6 gene and obesity?

There is not enough evidence to link the Alkbh6 gene to obesity.