Recombinant human AMACR
Cat.No. : | AMACR-3034H |
Product Overview : | a-Methylacyl CoA Racemase |
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Description : | This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011] |
Source : | N/A |
Species : | human |
Form : | Supplied as a liquid in 50mM Tris-Acetate, pH 7.5, 1mM EDTA, 20% glycerol. |
Purity : | Highly Purified~90% by RP-HPLC, FPLC, or reducing/non-reducing SDS-PAGE Silver Stain. Chromatographically purified. |
Applications : | Suitable for use in ELISA, Western Blot and Inhibition Assays. |
Notes : | Small volumes of AMACR recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice. |
Storage : | May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
Warning : | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Gene Name : | AMACR alpha-methylacyl-CoA racemase [ Homo sapiens ] |
Official Symbol : | AMACR |
Synonyms : | AMACR; alpha-methylacyl-CoA racemase; RACE; 2-methylacyl-CoA racemase; RM; CBAS4; AMACRD; |
Gene ID : | 23600 |
mRNA Refseq : | NM_001167595 |
Protein Refseq : | NP_001161067 |
MIM : | 604489 |
UniProt ID : | Q9UHK6 |
Chromosome Location : | 5p13.2-q11.1 |
Pathway : | Beta-oxidation of pristanoyl-CoA, organism-specific biosystem; Bile acid and bile salt metabolism, organism-specific biosystem; Bile acid biosynthesis, cholesterol =>cholate, organism-specific biosystem; Bile acid biosynthesis, cholesterol => cholate, |
Function : | alpha-methylacyl-CoA racemase activity; isomerase activity; |
Products Types
◆ Recombinant Protein | ||
AMACR-497M | Recombinant Mouse AMACR Protein, His (Fc)-Avi-tagged | +Inquiry |
AMACR-330H | Recombinant Human AMACR Protein, His (Fc)-Avi-tagged | +Inquiry |
AMACR-140R | Recombinant Rhesus Macaque AMACR Protein, His (Fc)-Avi-tagged | +Inquiry |
Amacr-1607M | Recombinant Mouse Amacr Protein, Myc/DDK-tagged | +Inquiry |
AMACR-107H | Recombinant Human AMACR, His-tagged | +Inquiry |
◆ Lysates | ||
AMACR-8888HCL | Recombinant Human AMACR 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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