Recombinant Human Annexin A6, His-tagged

• Cat.No.: ANXA6-1839H
• Product Overview: Recombinant human Annexin A6 fused to His-tag at N-terminus was expressed inE.coliand purified by using conventional chromatography techniques.MW = 78.0 kDa (693aa).

Specification

• Cat. No.: ANXA6-1839H
• Description: Annexin A6 belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin6 has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.
• Source: E.coli.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl.
• Purity: > 90% by SDS – PAGE.
• Concentration: 0.5 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MGSSHHHHHHSSGLVPRGSHMAKPA QGAKYRGSIHDFPGFDPNQDAEALY TAMKG FGSDKEAILDIITSRSNRQRQEVCQ SYKSLYGKDLIADLKYELTGKFERL IVGLM RPPA YCDAKEIKDAISGIGTDEKCLIEIL ASRTNEQMHQLVAAYKDAYERDLEA DIIGDT SGH FQKMLVVLLQGTREEDDVVSEDLVQ QDVQDLYEAGELKWGTDEAQFIYIL GNRS KQ HLRLVFDEYLKTTGKPIEASIRGEL SGDFEKLMLAVVKCIRSTPEYFAER L FKAMKGL G TR DNTLIRIMVS RSELDMLDIR EIFRTKYEKS LYSMIKNDTS GEYKKTLLKL SGGDDDAAGQ FFPEAAQVAYQMWELSAVAR VELKGTVRPA NDFNPDADAK ALRKAMKGLGTDEDTIIDIITHRSN VQRQQIRQTFKSHFGRDLMTDLKSE ISG DLAR LILGLMMPPAHYDAKQLKKAMEGAG TDEKALIEILATRTNAEIRAINEAY KED YHKSL ED ALS SDTSGHFRRI LISLATGHRE EGGENLDQAREDAQVAAEIL EIADTPSGDK TSLETRFMTILCTRSYPHLRRVFQE FIKMTNYDVEHTIKKEMSGDVRDAF VAIV QSV KNKPLFFADKLYKSMKGAGTDEKTL TRIMVSRSEIDLLNIRREFIEKYDK SLH QAIEG DTSGD FLKALLALCG GED.
• Storage: can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: ANXA6 annexin A6 [ Homo sapiens ]
• Synonyms: annexin A6; ANX6; CBP68; ANXA6; p68; p70; CPB-II; annexin-6; calelectrin; lipocortin VI; calphobindin II; calphobindin-II; chromobindin-20; annexin VI (p68); 67 kDa calelectrin; calcium-binding protein p68;Annexin VI; Lipocortin VI; Annexin-6; Protein III; Calphobindin-II; Chromobindin-20
• Gene ID: 309
• mRNA Refseq: NM_001155
• Protein Refseq: NP_001146
• MIM: 114070
• UniProt ID: P08133
• Chromosome Location: 5q32-q34
• Function: calcium ion binding; calcium-dependent phospholipid binding; protein binding