Recombinant Human AP1G2 Protein, His-tagged

• Cat.No.: AP1G2-179H
• Product Overview: Recombinant Human AP1G2 Protein (Met1-Leu272) with N-His tag was expressed in E. coli.

Specification

• Description: Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. This protein along with the complex is thought to function at some trafficking step in the complex pathways between the trans-Golgi network and the cell surface.
• Source: E. coli
• Species: Human
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 34.4 kDa
  Accurate Molecular Mass: 34 kDa
• Protein length: Met1-Leu272
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1 mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: AP1G2 adaptor related protein complex 1 subunit gamma 2 [ Homo sapiens (human) ]
• Official Symbol: AP1G2
• Synonyms: Ap1g2; adaptor related protein complex 1 subunit gamma 2; AP-1 complex subunit gamma-like 2; adaptor protein complex AP-1, gamma 2 subunit; adaptor-related protein complex 1, gamma 2 subunit
• Gene ID: 8906
• mRNA Refseq: NM_003917
• Protein Refseq: NP_003908
• MIM: 603534
• UniProt ID: O75843

Reviews

03/21/2021

AP1G2 activity is maintained for a very long time, can remain active for a long time, and is very stable and reliable.

03/14/2021

The catalytic activity is amazing, it can efficiently promote chemical reactions in a short time, and its catalytic effect is unmatched.

05/14/2020

The reproducibility of AP1G2 is very good, showing good production process and quality control.

Q&As

Can AP1G2 be directly absorbed through the skin?

AP1G2 cannot be directly absorbed through the skin because of its large molecular weight and it is not easy to penetrate the skin.

Does AP1G2 cause immune response?

Recombinant AP1G2 does not cause an immune response under normal use, but may cause an immune response under individual differences or abnormal use.

Can AP1G2 effectively improve brain hypoxia?

At present, it has not been found that the AP1G2 can effectively improve the brain hypoxia.

Is AP1G2 toxic?

The recombinant AP1G2 protein is not toxic under normal use, but may cause adverse reactions if the prescribed dosage is exceeded or abnormal reactions occur.

What are the prospects of AP1G2 in the medical field?

AP1G2 has a wide range of prospects in the medical field, and can be used in the production of biological drugs, disease diagnosis, treatment and prevention.

Does AP1G2 have the function of stimulating the immune system?

The AP1G2 does not stimulate the immune system because its action is mainly inside the cell.

Is AP1G2 used by intramuscular injection?

AP1G2 can be used by intramuscular injection, but should be performed by a medical professional and strictly controlled the amount and dosage of the drug.

What is the dose and use method of AP1G2 ?

The dosage and use method of AP1G2 should follow the corresponding clinical trial regulations and drug standards, and the specific guidance should be provided by a professional doctor.

Can AP1G2 be used in cancer therapy?

At present, no effective method of recombinant AP1G2 has been found in cancer treatment.

Which diseases can be treated with AP1G2 ?

There are currently no known recombinant AP1G2 treatment options for a specific disease.

What are the applications of AP1G2 ?

The AP1G2 can be used in clinical therapy, basic research, drug development and biologics production.

How is the research progress of AP1G2 ?

At present, AP1G2 has been widely used in biological product production, drug development and other fields, and relevant research progress is also gradually advancing.

What is the pharmacological mechanism of AP1G2 ?

Recombinant AP1G2 exerts pharmacological effects mainly by influencing membrane transport and local metabolism within cells.

What is the function of AP1G2 ?

The AP1G2 mainly acts on the transport between the cell membrane and the endoplasmic reticulum, and can affect the local metabolism and internal signaling of cells.

Does AP1G2 have other pharmacological effects?

AP1G2 has not been found to have any pharmacological effects other than cellular transport and local metabolism.