Recombinant Human AP2S1 Protein, His-tagged
Cat.No. : | AP2S1-187H |
Product Overview : | Recombinant Human AP2S1 Protein (Met1-Glu142) with N-His tag was expressed in E. coli. |
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Description : | One of two major clathrin-associated adaptor complexes, AP-2, is a heterotetramer which is associated with the plasma membrane. This complex is composed of two large chains, a medium chain, and a small chain. This gene encodes the small chain of this complex. Alternative splicing results in multiple transcript variants. |
Source : | E. coli |
Species : | Human |
Tag : | N-His |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 20.7 kDa Accurate Molecular Mass: 18 kDa |
Protein length : | Met1-Glu142 |
Purity : | > 90% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Storage Buffer : | PBS, pH7.4, containing 0.01% SKL, 1 mM DTT, 5% Trehalose and Proclin300. |
Reconstitution : | Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
Gene Name : | AP2S1 adaptor-related protein complex 2, sigma 1 subunit [ Homo sapiens (human) ] |
Official Symbol : | AP2S1 |
Synonyms : | AP2S1; adaptor-related protein complex 2, sigma 1 subunit; CLAPS2; AP-2 complex subunit sigma; sigma2-adaptin; HA2 17 kDa subunit; clathrin coat assembly protein AP17; clathrin coat-associated protein AP17; clathrin assembly protein 2 small chain; adaptor protein complex AP-2 subunit sigma; plasma membrane adaptor AP-2 17 kDa protein; adapter-related protein complex 2 sigma subunit; clathrin-associated/assembly/adaptor protein, small 2 (17kD); AP17; AP17-DELTA |
Gene ID : | 1175 |
mRNA Refseq : | NM_004069 |
Protein Refseq : | NP_004060 |
MIM : | 602242 |
UniProt ID : | P53680 |
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◆ Lysates | ||
AP2S1-8812HCL | Recombinant Human AP2S1 293 Cell Lysate | +Inquiry |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (19)
Ask a questionGenetic mutations in the AP2S1 have been shown to be associated with certain genetic diseases.
The AP2S1 is a three-dimensional structure composed of multiple amino acid residues.
AP2S1 is associated with various signaling pathways, such as EGFR signaling pathway and Notch signaling pathway.
There is currently insufficient evidence to support recombinant AP2S1 as a diagnostic marker for tumors.
The AP2S1 is involved in protein breakdown and transport in the cell.
The study of AP2S1 is of great significance for the research and development of new drugs, which can provide new ideas and directions for the discovery of drug targets.
Immunohistochemistry, Western blot and other methods can be used to detect the expression level of AP2S1 .
Some studies have shown that AP2S1 may play a role in tumorgenesis by influencing cell proliferation and metastasis.
There are currently no gene therapy studies involving recombinant AP2S1.
Recombinant protein AP2S1 may be a potential target for tumor therapy, but further research and validation are needed.
There has not been much research on the interaction of AP2S1 with drugs.
The AP2S1 may be one of the targets for drug development, but further studies are needed to confirm it.
The AP2S1 is widely distributed in the human body, including the nervous system and several organs.
The AP2S1 plays a key role in many diseases such as nervous system diseases and tumors.
The current drug development targeting AP2S1 is still in the preliminary stage, and further research and development is needed.
The association of recombinant AP2S1 with certain diseases may have genetic characteristics.
Recombinant AP2S1 protein is expressed in a variety of cell types.
Some studies have shown that recombinant AP2S1 may be involved in regulating synaptic transmission and other functions in nervous system diseases.
The AP2S1 may be a potential target for the treatment of this disease, but further studies are needed to confirm it.
Customer Reviews (4)
Write a reviewCatalytic activity of AP2S1 is very strong, which can significantly improve the selectivity and yield of chemical reactions, and its application potential is huge.
Experimenting with this recombinant protein allows me to focus more on experimental design and data analysis without worrying about the reproducibility of experimental results.
Quality of AP2S1 is consistent, and we're reassured.
Stability of AP2S1 is highly praised, and it can maintain its structural and functional stability even under various extreme environments, which is really impressive.
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