Recombinant Human AP5Z1 protein, GST-tagged
Cat.No. : | AP5Z1-664H |
Product Overview : | Human AP5Z1 full-length ORF ( AAH37399, 1 a.a. - 446 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | This gene was identified by genome-wide screen for genes involved in homologous recombination DNA double-strand break repair (HR-DSBR). The encoded protein was found in a complex with other proteins that have a role in HR-DSBR. Knockdown of this gene reduced homologous recombination, and mutations in this gene were found in patients with spastic paraplegia. It was concluded that this gene likely encodes a helicase (PMID:20613862). [provided by RefSeq, Jan 2011] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 74.8 kDa |
AA Sequence : | MAKVVVLSPGTLQEDQATLLSKRLV DWLRYASLQQGLPHSGGFFSTPRAR QPGPVTEVDGAVATDFFTVLSSGHR FTDDQWLNVQAFSMLRAWLLHSGPE GPGTLDTDDRSEQEGSTLSVISATS SAGRLLPPRERLREVAFEYCQRLIE QSNRRALRKGDSDLQKACLVEAVLV LDVLCRQDPSFLYRSLSCLKALHGR VRGDPASVRVLLPLAHFFLSHGEAA AVDSEAVYQHLFTRIPVEQFHSPML AFEFIQFCRDNLHLFSGHLSTLRLS FPNLFKFLAWNSPPLTSEFVALLPA LVDAGTALEMLHALLDLPCLTAVLD LQLRSAPAASERPLWDTSLRAPSCL EAFRDPQFQGLFQYLLRPKASGATE RLAPLHQLLQPMAGCARVAQCAQAV PTLLQAFFSAVTQVADGSLINQLAL LLLGRSDSLYPAPGYAAGVHR |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | AP5Z1 adaptor related protein complex 5 zeta 1 subunit [ Homo sapiens (human) ] |
Official Symbol : | AP5Z1 |
Synonyms : | AP5Z1; adaptor related protein complex 5 zeta 1 subunit; zeta; SPG48; KIAA0415; AP-5 complex subunit zeta-1; adapter-related protein complex 5 zeta subunit; adaptor-related protein complex 5 zeta subunit; zeta5 |
Gene ID : | 9907 |
mRNA Refseq : | NM_014855 |
Protein Refseq : | NP_055670 |
MIM : | 613653 |
UniProt ID : | O43299 |
Products Types
◆ Recombinant Protein | ||
AP5Z1-2481H | Recombinant Human AP5Z1 Protein, His (Fc)-Avi-tagged | +Inquiry |
AP5Z1-3545H | Recombinant Human AP5Z1, His-tagged | +Inquiry |
AP5Z1-1196H | Recombinant Human AP5Z1 | +Inquiry |
◆ Lysates | ||
AP5Z1-359HCL | Recombinant Human AP5Z1 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (15)
Ask a questionThe -AP5Z1 may interact with other proteins, and these interactions may be the key to understanding the function of the AP5Z1 signaling pathway.
The AP5Z1 is a protein synthesized by recombinant DNA technology, which is related to the AP5Z1 gene and has a specific biological function.
A common method of producing AP5Z1 is by introducing the AP5Z1 gene into the host cell and using the protein synthesis mechanism within the cell to express the target protein.
The recombinant -AP5Z1 protein can be used to treat diseases related to the AP5Z1 signaling pathway, such as tumors, immune system diseases, etc.
The -AP5Z1 may serve as a potential link in gene therapy, but further research and experimental verification are still needed.
The AP5Z1 may be a potential immunotherapy agent, but further clinical studies are needed to evaluate its efficacy and safety.
There have been no clear reports of side effects associated with AP5Z1 , but a medical professional should be consulted before use.
The stability of the -AP5Z1 may vary depending on different expression systems and storage conditions, and it is necessary to ensure that it is stored and used under appropriate conditions.
The ability of the -AP5Z1 to bind to a specific antibody may be related to the specificity of the antibody, which can be evaluated by relevant experiments.
The AP5Z1 can help researchers to further study the function of AP5Z1 and its interaction with other proteins, thus advancing the scientific development of related fields.
The pharmacokinetics of the -AP5Z1 require further studies to evaluate its distribution, metabolism and excretion in vivo.
The -AP5Z1 can target cancer cells and inhibit their growth and spread, thus having potential anti-cancer effects.
The AP5Z1 may be used to develop in vitro diagnostic kits, but it needs to be validated and evaluated accordingly.
Batch differences in the of -AP5Z1 may exist, which may be caused by differences in production process, purification method and quality control.
The long-term stability of the AP5Z1 needs to be evaluated under suitable storage conditions, such as cryogenic storage and protection from light, which can help maintain its stability.
Customer Reviews (4)
Write a reviewLower limit of detection of AP5Z1 in Western blot was significantly reduced.
AP5Z1 produced by them has good stability and long-term preservation without problems.
Using AP5Z1 significantly improved the efficiency of my experiments and reduced unnecessary waste of time.
Catalytic activity of AP5Z1 is amazing, and it can achieve efficient catalysis under mild conditions, and its mild nature is appreciated.
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