Recombinant Human APCDD1L 293 Cell Lysate

• Cat.No.: APCDD1L-8799HCL

Specification

• Description: Antigen standard for adenomatosis polyposis coli down-regulated 1-like (APCDD1L) is a lysate prepared from HEK293T cells transiently transfected with a TrueORF gene-carrying pCMV plasmid and then lysed in RIPA Buffer. Protein concentration was determined using a colorimetric assay. The antigen control carries a C-terminal Myc/DDK tag for detection.
• Source: HEK 293 cells
• Species: Human
• Components: This product includes 3 vials: 1 vial of gene-specific cell lysate, 1 vial of control vector cell lysate, and 1 vial of loading buffer. Each lysate vial contains 0.1 mg lysate in 0.1 ml (1 mg/ml) of RIPA Buffer (50 mM Tris-HCl pH7.5, 250 mM NaCl, 5 mM EDTA, 50 mM NaF, 1% NP40). The loading buffer vial contains 0.5 ml 2X SDS Loading Buffer (125 mM Tris-Cl, pH6.8, 10% glycerol, 4% SDS, 0.002% Bromophenol blue, 5% beta-mercaptoethanol).
• Size: 0.1 mg
• Storage Instruction: Store at -80°C. Minimize freeze-thaw cycles. After addition of 2X SDS Loading Buffer, the lysates can be stored at -20°C. Product is guaranteed 6 months from the date of shipment.
• Applications: ELISA, WB, IP. WB: Mix equal volume of lysates with 2X SDS Loading Buffer. Boil the mixture for 10 min before loading (for membrane protein lysates, incubate the mixture at room temperature for 30 min). Load 5 ug lysate per lane.

Gene Information

• Gene Name: APCDD1L?adenomatosis polyposis coli down-regulated 1-like [?Homo sapiens?(human) ]
• Official Symbol: APCDD1L
• Synonyms: APCDD1L; adenomatosis polyposis coli down-regulated 1-like; protein APCDD1-like; adenomatosis polyposis coli down-regulated 1 protein-like
• Gene ID: 164284
• mRNA Refseq: NM_153360
• Protein Refseq: NP_699191
• UniProt ID: Q8NCL9
• Chromosome Location: 20q13.32

Reviews

05/20/2022

Reproducibility of APCDD1L is very good, which can ensure the safety of the experiment and avoid unnecessary risks.

06/17/2021

Short half-life and high clearance of APCDD1L means that the drug can quickly reach an effective concentration in the body and be quickly cleared with fewer side effects.

02/19/2021

The band clarity of APCDD1L in Western blot is very high, which improves the reliability of the experiment.

02/01/2021

Experiments using APCDD1L can be more focused on experimental design and data analysis without worrying about the stability of experimental results.

01/10/2020

The production process of APCDD1L achieves zero pollution and has a positive impact on the environment, demonstrating its commitment to environmental protection.

Q&As

What clinical problems has the study of APCDD1L provided a new breakthrough?

The study of APCDD1L provides new clues and theoretical support for understanding the mechanism of tumor formation, the pathogenesis of cardiovascular diseases and the developmental disorders of nervous system.

Can APCDD1L be used as a therapeutic target for tumors?

Further research is needed to explore, and there is no clear evidence that APCDD1L can be directly used in the treatment of tumors.

In which diseases may APCDD1L play a key role?

APCDD1L is closely related to the occurrence and development of many diseases, including tumor, cardiovascular disease and neurodevelopmental disorders.

How does APCDD1L intervene in cardiovascular disease?

Recombinant APCDD1L may influence the development of cardiovascular diseases by regulating cell proliferation, migration and angiogenesis.

Can APCDD1L be used for early diagnosis of cardiovascular disease?

The early diagnostic application of APCDD1L still faces technical and experimental challenges, and further research is needed at present.

What is the association between APCDD1L and neurodevelopmental disorders?

APCDD1L is involved in the regulation of cell polarity and migration during neurodevelopment, and its abnormal expression may lead to neurodevelopmental disorders.

What is the relationship between APCDD1L and tumor?

The expression of APCDD1L was found to be abnormal in some tumors, which may be involved in the genesis and development of tumors.

What is APCDD1L ?

APCDD1L is a protein encoded by human gene APCDD1L, which plays an important role in cell signaling and regulation of development.

Does APCDD1L have clinical application potential?

The APCDD1L is still in its infancy, but has the potential to be a target molecule for the diagnosis and treatment of certain diseases.

What is the main function of APCDD1L ?

The APCDD1L is involved in the proliferation, differentiation and migration of gallbladder epithelial cells and plays an important role in normal tissue development and maintenance of tissue structure.